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FB:CrebA

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) CrebA ( synonyms: BBF-2, BBF2_DROME, BOX B Binding Factor-2, Bbbf2, BcDNA:SD05937, Box B-binding factor 2, CG7450, CRE-BP, CREB, CREB-A, CREB-a, CREBA, Creb, Creb A, Creb-A, cAMP response element binding protein, cAMP response element binding protein A, creb, crebA, cyclic AMP response element binding protein, dCREB-A, dCREBA, dCreb-A, dCrebA, l(3)03576 )
Protein Name(s) Cyclic-AMP response element binding protein A,
External Links
FB FBgn0004396

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001158

enhancer sequence-specific DNA binding

FB:FBrf0212217
PMID:21041443[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0056139
PMID:1532159[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0123931

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0057239
PMID:1508208[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0123931

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0056139
PMID:1532159[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0123931

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0207774
PMID:19253394[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0006366

transcription from RNA polymerase II promoter

FB:FBrf0123931

NAS: Non-traceable Author Statement

P

From FB

GO:0007431

salivary gland development

FB:FBrf0091006
PMID:9006079[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007431

salivary gland development

FB:FBrf0159337
PMID:12742168[6]

TAS: Traceable Author Statement

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0139594
PMID:11598957[7]

NAS: Non-traceable Author Statement

P

From FB

GO:0008363

larval chitin-based cuticle development

FB:FBrf0187447
PMID:15901661[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009953

dorsal/ventral pattern formation

FB:FBrf0091006
PMID:9006079[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0000490

P

From FB

GO:0035293

chitin-based larval cuticle pattern formation

FB:FBrf0091006
PMID:9006079[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035293

chitin-based larval cuticle pattern formation

FB:FBrf0187447
PMID:15901661[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0152056
PMID:12176927[9]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0057239
PMID:1508208[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0045893

positive regulation of transcription, DNA-dependent

FB:FBrf0212217
PMID:21041443[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0057239
PMID:1508208[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0046983

protein dimerization activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011616

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Fox RM et al. (2010) The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J Cell Biol 191: 479-92 PubMed GONUTS page
  2. 2.0 2.1 Abel T et al. (1992) A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. Genes Dev 6: 466-80 PubMed GONUTS page
  3. 3.0 3.1 3.2 Smolik SM et al. (1992) A cyclic AMP-responsive element-binding transcriptional activator in Drosophila melanogaster, dCREB-A, is a member of the leucine zipper family. Mol Cell Biol 12: 4123-31 PubMed GONUTS page
  4. Jattani R et al. (2009) Deficiency screen identifies a novel role for beta 2 tubulin in salivary gland and myoblast migration in the Drosophila embryo. Dev Dyn 238: 853-63 PubMed GONUTS page
  5. 5.0 5.1 5.2 Andrew DJ et al. (1997) The Drosophila dCREB-A gene is required for dorsal/ventral patterning of the larval cuticle. Development 124: 181-93 PubMed GONUTS page
  6. Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
  7. Bradley PL et al. (2001) Organ formation in Drosophila: specification and morphogenesis of the salivary gland. Bioessays 23: 901-11 PubMed GONUTS page
  8. 8.0 8.1 Abrams EW & Andrew DJ (2005) CrebA regulates secretory activity in the Drosophila salivary gland and epidermis. Development 132: 2743-58 PubMed GONUTS page
  9. Fassler J et al. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-200 PubMed GONUTS page
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