Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:CkIalpha

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) CkIalpha ( synonyms: CG2028, CK I, CK1, CK1a, CK1alpha, CKI, CKI alpha, CKIa, CKIalpha, Casein Kinase 1, Casein kinase 1, Casein kinase I, CkIa, PKA-C, anon-WO03040301.93, anon-WO03040301.95, caesin kinase I alpha, casein kinase 1, casein kinase 1a, casein kinase I, casein kinase Ialpha, ck1a, ck1alpha, dmCK1, dmckI, l(1)G0492 )
Protein Name(s) Casein kinase Ialpha,
External Links
FB FBgn0015024

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000902

cell morphogenesis

FB:FBrf0212211
PMID:21041442[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0002121

inter-male aggressive behavior

FB:FBrf0208496
PMID:19519879[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004672

protein kinase activity

FB:FBrf0089811
PMID:8832407[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0089811
PMID:8832407[3]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P48729

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0120101

NAS: Non-traceable Author Statement

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0132098
PMID:10908587[4]

NAS: Non-traceable Author Statement

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0156812

NAS: Non-traceable Author Statement

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From FB

GO:0005634

nucleus

FB:FBrf0089811
PMID:8832407[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0193614
PMID:16987508[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0089811
PMID:8832407[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0156812

NAS: Non-traceable Author Statement

C

From FB

GO:0005737

cytoplasm

FB:FBrf0193614
PMID:16987508[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0006281

DNA repair

FB:FBrf0089811
PMID:8832407[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0156812

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0190207
PMID:16326393[6]

IDA: Inferred from Direct Assay

P

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0161622

TAS: Traceable Author Statement

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0161622

TAS: Traceable Author Statement

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030111

regulation of Wnt receptor signaling pathway

FB:FBrf0193614
PMID:16987508[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030162

regulation of proteolysis

FB:FBrf0151999
PMID:12231619[8]

TAS: Traceable Author Statement

P

From FB

GO:0030163

protein catabolic process

FB:FBrf0151527
PMID:12127767[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0045879

negative regulation of smoothened signaling pathway

FB:FBrf0159322
PMID:12663920[10]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. D'Ambrosio MV & Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191: 471-8 PubMed GONUTS page
  2. Edwards AC et al. (2009) Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol 7: 29 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Santos JA et al. (1996) The casein kinase 1 alpha gene of Drosophila melanogaster is developmentally regulated and the kinase activity of the protein induced by DNA damage. J Cell Sci 109 ( Pt 7): 1847-56 PubMed GONUTS page
  4. 4.0 4.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  5. 5.0 5.1 5.2 Zhang L et al. (2006) Regulation of wingless signaling by the CKI family in Drosophila limb development. Dev Biol 299: 221-37 PubMed GONUTS page
  6. Jia J et al. (2005) Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing. Dev Cell 9: 819-30 PubMed GONUTS page
  7. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
  8. Jiang J (2002) Degrading Ci: who is Cul-pable? Genes Dev 16: 2315-21 PubMed GONUTS page
  9. Cadigan KM (2002) Wnt signaling--20 years and counting. Trends Genet 18: 340-2 PubMed GONUTS page
  10. Lum L et al. (2003) Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299: 2039-45 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox