GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:CkIIalpha
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | CkIIalpha ( synonyms: CG17520, CJIIalpha, CK II, CK-2, CK-II, CK-II alpha, CK2, CK2 alpha, CK2-alpha, CK2a, CK2alpha, CKII, CKII alpha, CKII-alpha, CKIIa, CKIIalfa, CKIIalpha, Casein kinase II, Casein kinase II-alpha subunit, Cask-II-a, Ck2alpha, CkII, DmCK2alpha, DmCKIIalpha, NAP1-kinase, Tik, Timekeeper, alpha subunit of Drosophila casein kinase II, alphaCK2, anon-WO02059370.53, casein kinase 2, casein kinase II, ckIIalpha, dCK2alpha, dCKII, dCKII alpha, protein kinase CK2 ) | |
| Protein Name(s) | Casein kinase II alpha subunit, | |
| External Links | ||
| FB | FBgn0000258 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0039682 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0041214 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0046975 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:U51866 |
F |
From FB |
||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0123451 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0152220 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0145118 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015025 |
F |
From FB |
||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0039682 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0152220 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005829 |
cytosol |
FB:FBrf0039682 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005956 |
protein kinase CK2 complex |
FB:FBrf0039682 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005956 |
protein kinase CK2 complex |
FB:FBrf0041214 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005956 |
protein kinase CK2 complex |
FB:FBrf0046975 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005956 |
protein kinase CK2 complex |
FB:FBrf0123451 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0039682 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0046975 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0123451 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007067 |
mitosis |
FB:FBrf0207149 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007228 |
positive regulation of hh target transcription factor activity |
FB:FBrf0214177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0210319 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0191049 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0093787 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0022416 |
chaeta development |
FB:FBrf0193054 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031397 |
negative regulation of protein ubiquitination |
FB:FBrf0214177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031647 |
regulation of protein stability |
FB:FBrf0214177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045475 |
locomotor rhythm |
FB:FBrf0155498 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045475 |
locomotor rhythm |
FB:FBrf0206514 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045880 |
positive regulation of smoothened signaling pathway |
FB:FBrf0214177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046331 |
lateral inhibition |
FB:FBrf0193054 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0174882 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0193054 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Glover CV et al. (1983) Purification and characterization of a type II casein kinase from Drosophila melanogaster. J Biol Chem 258: 3258-65 PubMed GONUTS page
- ↑ 3.0 3.1 Dahmus GK et al. (1984) Similarities in structure and function of calf thymus and Drosophila casein kinase II. J Biol Chem 259: 9001-6 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Saxena A et al. (1987) Isolation and sequencing of cDNA clones encoding alpha and beta subunits of Drosophila melanogaster casein kinase II. Mol Cell Biol 7: 3409-17 PubMed GONUTS page
- ↑ 5.0 5.1 Siomi MC et al. (2002) Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties. Mol Cell Biol 22: 8438-47 PubMed GONUTS page
- ↑ Kalive M et al. (2001) A gene located at 72A in Drosophila melanogaster encodes a novel zinc-finger protein that interacts with protein kinase CK2. Mol Cell Biochem 227: 99-105 PubMed GONUTS page
- ↑ Ducat D et al. (2008) Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell 19: 3097-110 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Jia H et al. (2010) Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J Biol Chem 285: 37218-26 PubMed GONUTS page
- ↑ Berger J et al. (2008) Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system. PLoS Genet 4: e1000085 PubMed GONUTS page
- ↑ Lin JM et al. (2005) In vivo circadian function of casein kinase 2 phosphorylation sites in Drosophila PERIOD. J Neurosci 25: 11175-83 PubMed GONUTS page
- ↑ Willert K et al. (1997) Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J 16: 3089-96 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Bose A et al. (2006) Drosophila CK2 regulates lateral-inhibition during eye and bristle development. Mech Dev 123: 649-64 PubMed GONUTS page
- ↑ Lin JM et al. (2002) A role for casein kinase 2alpha in the Drosophila circadian clock. Nature 420: 816-20 PubMed GONUTS page
- ↑ Akten B et al. (2009) Ribosomal s6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator. J Neurosci 29: 466-75 PubMed GONUTS page
- ↑ Karandikar UC et al. (2004) Drosophila CK2 regulates eye morphogenesis via phosphorylation of E(spl)M8. Mech Dev 121: 273-86 PubMed GONUTS page
