GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Chc
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Chc ( synonyms: CG9012, CHC, CLH, Cla, Clathrin, Clathrin hc, D-Chc, chc, clathrin, clathrin heavy chain, dCHC, l(1)13Fb, l(1)G0438, l(1)VI ) | |
| Protein Name(s) | Clathrin heavy chain, | |
| External Links | ||
| FB | FBgn0000319 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005198 |
structural molecule activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0210180 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000183 |
F |
From FB |
||
| GO:0005802 |
trans-Golgi network |
FB:FBrf0209912 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005811 |
lipid particle |
FB:FBrf0200342 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0208955 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005905 |
coated pit |
FB:FBrf0108281 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0006886 |
intracellular protein transport |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000547 |
P |
From FB |
||
| GO:0006897 |
endocytosis |
FB:FBrf0210409 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007269 |
neurotransmitter secretion |
FB:FBrf0108281 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007291 |
sperm individualization |
FB:FBrf0102829 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008021 |
synaptic vesicle |
FB:FBrf0108281 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0016183 |
synaptic vesicle coating |
FB:FBrf0108281 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016183 |
synaptic vesicle coating |
FB:FBrf0123929 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030125 |
clathrin vesicle coat |
FB:FBrf0108281 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0030129 |
clathrin coat of synaptic vesicle |
FB:FBrf0123929 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0030130 |
clathrin coat of trans-Golgi network vesicle |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0030132 |
clathrin coat of coated pit |
FB:FBrf0123929 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0030132 |
clathrin coat of coated pit |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0030135 |
coated vesicle |
FB:FBrf0108281 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0030198 |
extracellular matrix organization |
FB:FBrf0201678 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031410 |
cytoplasmic vesicle |
FB:FBrf0208955 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0033227 |
dsRNA transport |
FB:FBrf0192229 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035002 |
liquid clearance, open tracheal system |
FB:FBrf0201678 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035159 |
regulation of tube length, open tracheal system |
FB:FBrf0201678 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040008 |
regulation of growth |
FB:FBrf0210409 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0044459 |
plasma membrane part |
FB:FBrf0209912 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045747 |
positive regulation of Notch signaling pathway |
FB:FBrf0210409 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045807 |
positive regulation of endocytosis |
FB:FBrf0207263 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046667 |
compound eye retinal cell programmed cell death |
FB:FBrf0207263 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
FB:FBrf0209912 |
IDA: Inferred from Direct Assay |
C |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Li X et al. (2010) Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling. EMBO J 29: 992-1006 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kametaka S et al. (2010) Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster. J Cell Sci 123: 460-71 PubMed GONUTS page
- ↑ 3.0 3.1 Wingen C et al. (2009) Expression and localization of clathrin heavy chain in Drosophila melanogaster. Gene Expr Patterns 9: 549-54 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Stimson DT & Ramaswami M (1999) Vesicle recycling at the Drosophila neuromuscular junction. Int Rev Neurobiol 43: 163-89 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Windler SL & Bilder D (2010) Endocytic internalization routes required for delta/notch signaling. Curr Biol 20: 538-43 PubMed GONUTS page
- ↑ Fabrizio JJ et al. (1998) Genetic dissection of sperm individualization in Drosophila melanogaster. Development 125: 1833-43 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Behr M et al. (2007) Wurst is essential for airway clearance and respiratory-tube size control. Nat Cell Biol 9: 847-53 PubMed GONUTS page
- ↑ Saleh MC et al. (2006) The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol 8: 793-802 PubMed GONUTS page
- ↑ 9.0 9.1 Peralta S et al. (2009) Notch down-regulation by endocytosis is essential for pigment cell determination and survival in the Drosophila retina. Mech Dev 126: 256-69 PubMed GONUTS page
