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FB:Ced-12

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Ced-12 ( synonyms: CG5336, Ced12, Dced-12, ELMO, Elmo, ced-12, dced-12, elmo, engulfment and cell motility )
Protein Name(s) Ced-12,
External Links
FB FBgn0032409

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005488

binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011989

F

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006909

phagocytosis

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006816

P

From FB

GO:0007015

actin filament organization

FB:FBrf0157328
PMID:11703939[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0200493
PMID:17637670[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0202723
PMID:18163987[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007520

myoblast fusion

FB:FBrf0202723
PMID:18163987[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016477

cell migration

FB:FBrf0157328
PMID:11703939[2]

IGI: Inferred from Genetic Interaction

WP:CE27228

P

From FB

GO:0032863

activation of Rac GTPase activity

FB:FBrf0202723
PMID:18163987[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0010333
FB:FBgn0015513

P

From FB

GO:0032863

activation of Rac GTPase activity

FB:FBrf0202723
PMID:18163987[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0010333
FB:FBgn0015513
FB:FBgn0014011

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  2. 2.0 2.1 Zhou Z et al. (2001) The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev Cell 1: 477-89 PubMed GONUTS page
  3. Bianco A et al. (2007) Two distinct modes of guidance signalling during collective migration of border cells. Nature 448: 362-5 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Geisbrecht ER et al. (2008) Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization. Dev Biol 314: 137-49 PubMed GONUTS page
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