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FB:Caki

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) CASK ( synonyms: CAKI, CAMGUK, CG13412, CG13413, CG6703, CMG, CMG/CASK, Caki, Calcium/calmodulin-dependent protein kinase, CamGUK, CamguK, Camguk, Camguk/CASK adaptor protein, Cask, Cmg, DLin-2, caki, calmodulin-dependent kinase, camguk, cmg, dCASK )
Protein Name(s) CASK ortholog,
External Links
FB FBgn0013759

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004674

protein serine/threonine kinase activity

FB:FBrf0132098
PMID:10908587[1]

NAS: Non-traceable Author Statement

F

From FB

GO:0004683

calmodulin-dependent protein kinase activity

FB:FBrf0087589
PMID:8617233[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0004683

calmodulin-dependent protein kinase activity

FB:FBrf0087589
PMID:8617233[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From FB

GO:0005954

calcium- and calmodulin-dependent protein kinase complex

FB:FBrf0087589
PMID:8617233[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

P

From FB

GO:0007155

cell adhesion

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007163

establishment or maintenance of cell polarity

FB:FBrf0159915
PMID:12766944[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0007269

neurotransmitter secretion

FB:FBrf0127207
PMID:10798391[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0007628

adult walking behavior

FB:FBrf0087589
PMID:8617233[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008049

male courtship behavior

FB:FBrf0212754
PMID:21059886[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008344

adult locomotory behavior

FB:FBrf0212754
PMID:21059886[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008360

regulation of cell shape

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016080

synaptic vesicle targeting

FB:FBrf0127207
PMID:10798391[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0016081

synaptic vesicle docking involved in exocytosis

FB:FBrf0127207
PMID:10798391[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0046331

lateral inhibition

FB:FBrf0214518

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046928

regulation of neurotransmitter secretion

FB:FBrf0187895
PMID:15872064[7]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Martin JR & Ollo R (1996) A new Drosophila Ca2+/calmodulin-dependent protein kinase (Caki) is localized in the central nervous system and implicated in walking speed. EMBO J 15: 1865-76 PubMed GONUTS page
  3. 3.0 3.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
  4. Humbert P et al. (2003) Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. Bioessays 25: 542-53 PubMed GONUTS page
  5. 5.0 5.1 5.2 Lloyd TE et al. (2000) A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron 26: 45-50 PubMed GONUTS page
  6. 6.0 6.1 Slawson JB et al. (2011) Central regulation of locomotor behavior of Drosophila melanogaster depends on a CASK isoform containing CaMK-like and L27 domains. Genetics 187: 171-84 PubMed GONUTS page
  7. Zordan MA et al. (2005) Drosophila CAKI/CMG protein, a homolog of human CASK, is essential for regulation of neurotransmitter vesicle release. J Neurophysiol 94: 1074-83 PubMed GONUTS page
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