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FB:CDC45L

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) CDC45L ( synonyms: CDC45, CG3658, Cdc45, D, DmCdc45, EG:BACR7A4.11, Transcription unit D, anon-1Ec, cdc45, dCDC45 )
Protein Name(s) CDC45L,
External Links
FB FBgn0026143

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF062494

F

From FB

GO:0003682

chromatin binding

FB:FBrf0129950
PMID:11024168[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0005634

nucleus

FB:FBrf0129950
PMID:11024168[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005656

pre-replicative complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF062494

C

From FB

GO:0005656

pre-replicative complex

FB:FBrf0129950
PMID:11024168[1]

IPI: Inferred from Physical Interaction

FB:FBgn0015929

C

From FB

GO:0005656

pre-replicative complex

FB:FBrf0129950
PMID:11024168[1]

IPI: Inferred from Physical Interaction

FB:FBgn0017577

C

From FB

GO:0005656

pre-replicative complex

FB:FBrf0129950
PMID:11024168[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:1739

C

From FB

GO:0005656

pre-replicative complex

FB:FBrf0129950
PMID:11024168[1]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0004093

C

From FB

GO:0005737

cytoplasm

FB:FBrf0129950
PMID:11024168[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006260

DNA replication

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF062494

P

From FB

GO:0006260

DNA replication

FB:FBrf0129950
PMID:11024168[1]

IPI: Inferred from Physical Interaction

FB:FBgn0015929

P

From FB

GO:0006260

DNA replication

FB:FBrf0129950
PMID:11024168[1]

IPI: Inferred from Physical Interaction

FB:FBgn0017577

P

From FB

GO:0006270

DNA-dependent DNA replication initiation

FB:FBrf0129950
PMID:11024168[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:1739

P

From FB

GO:0006270

DNA-dependent DNA replication initiation

FB:FBrf0129950
PMID:11024168[1]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0004093

P

From FB

GO:0006277

DNA amplification

FB:FBrf0129950
PMID:11024168[1]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0261530

P

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030261

chromosome condensation

FB:FBrf0160452
PMID:12808023[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045750

positive regulation of S phase of mitotic cell cycle

FB:FBrf0193013
PMID:16798881[4]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0043138

3'-5' DNA helicase activity

FB:FBrf0193013
PMID:16798881[4]

IDA: Inferred from Direct Assay

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Loebel D et al. (2000) Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification. Nucleic Acids Res 28: 3897-903 PubMed GONUTS page
  2. 2.0 2.1 Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
  3. Christensen TW & Tye BK (2003) Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation. Mol Biol Cell 14: 2206-15 PubMed GONUTS page
  4. 4.0 4.1 Moyer SE et al. (2006) Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc Natl Acad Sci U S A 103: 10236-41 PubMed GONUTS page
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