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FB:Buffy

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Buffy ( synonyms: 48A-E Bcl-2-like, BUFFY, Bcl-2-48AE, Buffy/Borg2, Buffy/DBorg-2, Buffy/dBorg-2, CG8238, Dbx, Drob2, buffy, dBORG-2/BUFFY, dBorg-2, dBorg2, dbuffy )
Protein Name(s) Buffy,
External Links
FB FBgn0040491

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006915

apoptotic process

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:88139

P

From FB

GO:0006915

apoptotic process

FB:FBrf0127019
PMID:10801447[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:990

P

From FB

GO:0006915

apoptotic process

FB:FBrf0173268
PMID:12938178[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0006916

anti-apoptosis

FB:FBrf0160857
PMID:12853472[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0003997

P

From FB

GO:0006916

anti-apoptosis

FB:FBrf0160857
PMID:12853472[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0011706

P

From FB

GO:0006916

anti-apoptosis

FB:FBrf0160857
PMID:12853472[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0015946

P

From FB

GO:0006916

anti-apoptosis

FB:FBrf0160857
PMID:12853472[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0260635

P

From FB

GO:0006916

anti-apoptosis

FB:FBrf0160857
PMID:12853472[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0130139
PMID:10908589[4]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:5802578

P

From FB

GO:0012501

programmed cell death

FB:FBrf0149068
PMID:12072176[5]

TAS: Traceable Author Statement

P

From FB

GO:0042981

regulation of apoptotic process

FB:FBrf0149068
PMID:12072176[5]

TAS: Traceable Author Statement

P

From FB

GO:0042981

regulation of apoptotic process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000712
InterPro:IPR002475

P

From FB

GO:0043068

positive regulation of programmed cell death

FB:FBrf0212047
PMID:20558283[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0015946

P

From FB

GO:0043068

positive regulation of programmed cell death

FB:FBrf0212047
PMID:20558283[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Brachmann CB et al. (2000) The Drosophila bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation. Curr Biol 10: 547-50 PubMed GONUTS page
  2. Lawen A (2003) Apoptosis-an introduction. Bioessays 25: 888-96 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Quinn L et al. (2003) Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions. EMBO J 22: 3568-79 PubMed GONUTS page
  4. Vernooy SY et al. (2000) Cell death regulation in Drosophila: conservation of mechanism and unique insights. J Cell Biol 150: F69-76 PubMed GONUTS page
  5. 5.0 5.1 Richardson H & Kumar S (2002) Death to flies: Drosophila as a model system to study programmed cell death. J Immunol Methods 265: 21-38 PubMed GONUTS page
  6. 6.0 6.1 Wu JN et al. (2010) grim promotes programmed cell death of Drosophila microchaete glial cells. Mech Dev 127: 407-17 PubMed GONUTS page
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