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FB:Btk29A

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Btk29A ( synonyms: C-src2, C-src4, CG18355, CG8049, CT2415, CT41718, DSrc28, DTec29, Dm SRC2, Dsrc28C, Dsrc29A, S13, SRC 29A, Src oncogene 29A, Src2, Src29A, Tec, Tec29, Tec29A, btk, btk29A, btk29a, c-src/fps, dsrc29A, fic, fickle, src-4, src2, src28C, src4, tec29 )
Protein Name(s) Btk family kinase at 29A,
External Links
FB FBgn0003502

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004713

protein tyrosine kinase activity

FB:FBrf0046962
PMID:3110602[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q06187

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0056063
PMID:1397284[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P42680

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0123460

NAS: Non-traceable Author Statement

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From FB

GO:0005543

phospholipid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From FB

GO:0005737

cytoplasm

FB:FBrf0051511
PMID:2108066[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0051511
PMID:2108066[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0046962
PMID:3110602[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q06187

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0123460

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0007254

JNK cascade

FB:FBrf0151280
PMID:12147138[5]

TAS: Traceable Author Statement

P

From FB

GO:0007300

ovarian nurse cell to oocyte transport

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007301

female germline ring canal formation

FB:FBrf0102811
PMID:9660965[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007301

female germline ring canal formation

FB:FBrf0102812
PMID:9660966[8]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007301

female germline ring canal formation

FB:FBrf0103249
PMID:9655810[9]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007349

cellularization

FB:FBrf0167540
PMID:14736750[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[5]

TAS: Traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0190308
PMID:16469972[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0187454
PMID:16000381[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007485

imaginal disc-derived male genitalia development

FB:FBrf0108136
PMID:10330180[13]

IDA: Inferred from Direct Assay

P

From FB

GO:0007485

imaginal disc-derived male genitalia development

FB:FBrf0108136
PMID:10330180[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007619

courtship behavior

FB:FBrf0141665
PMID:11715043[14]

NAS: Non-traceable Author Statement

P

From FB

GO:0008258

head involution

FB:FBrf0102811
PMID:9660965[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0108136
PMID:10330180[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030717

karyosome formation

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030723

ovarian fusome organization

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030833

regulation of actin filament polymerization

FB:FBrf0187454
PMID:16000381[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035556

intracellular signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001562

P

From FB

GO:0042023

DNA endoreduplication

FB:FBrf0187454
PMID:16000381[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045172

germline ring canal

FB:FBrf0102812
PMID:9660966[8]

IDA: Inferred from Direct Assay

C

From FB

GO:0045172

germline ring canal

FB:FBrf0103249
PMID:9655810[9]

IDA: Inferred from Direct Assay

C

From FB

GO:0045172

germline ring canal

FB:FBrf0132360
PMID:11131529[15]

TAS: Traceable Author Statement

C

From FB

GO:0046960

sensitization

FB:FBrf0201139
PMID:17464798[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Gregory RJ et al. (1987) Primary sequence and developmental expression of a novel Drosophila melanogaster src gene. Mol Cell Biol 7: 2119-27 PubMed GONUTS page
  2. Theroux SJ & Wadsworth SC (1992) Protein-tyrosine kinase activity of alternate protein products of the Drosophila Dsrc28C locus. FEBS Lett 311: 1-6 PubMed GONUTS page
  3. 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  4. 4.0 4.1 Wadsworth SC et al. (1990) Differential expression of alternate forms of a Drosophila src protein during embryonic and larval tissue differentiation. Dev Biol 138: 296-312 PubMed GONUTS page
  5. 5.0 5.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Djagaeva I et al. (2005) Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis. Dev Biol 284: 143-56 PubMed GONUTS page
  7. 7.0 7.1 Roulier EM et al. (1998) The Tec29 tyrosine kinase is required during Drosophila embryogenesis and interacts with Src64 in ring canal development. Mol Cell 1: 819-29 PubMed GONUTS page
  8. 8.0 8.1 Guarnieri DJ et al. (1998) SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth. Mol Cell 1: 831-40 PubMed GONUTS page
  9. 9.0 9.1 Dodson GS et al. (1998) Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis. Development 125: 2883-92 PubMed GONUTS page
  10. Thomas JH & Wieschaus E (2004) src64 and tec29 are required for microfilament contraction during Drosophila cellularization. Development 131: 863-71 PubMed GONUTS page
  11. Matusek T et al. (2006) The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton. Development 133: 957-66 PubMed GONUTS page
  12. 12.0 12.1 12.2 Chandrasekaran V & Beckendorf SK (2005) Tec29 controls actin remodeling and endoreplication during invagination of the Drosophila embryonic salivary glands. Development 132: 3515-24 PubMed GONUTS page
  13. 13.0 13.1 13.2 Baba K et al. (1999) The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation. Mol Cell Biol 19: 4405-13 PubMed GONUTS page
  14. Sokolowski MB (2001) Drosophila: genetics meets behaviour. Nat Rev Genet 2: 879-90 PubMed GONUTS page
  15. Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
  16. Asztalos Z et al. (2007) The fickle mutation of a cytoplasmic tyrosine kinase effects sensitization but not dishabituation in Drosophila melanogaster. J Neurogenet 21: 59-71 PubMed GONUTS page
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