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FB:BG4

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) BG4 ( synonyms: CG12297, FADD, Fadd, dFADD, dFadd, dfadd )
Protein Name(s) BG4,
External Links
FB FBgn0038928

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005123

death receptor binding

FB:FBrf0130715

NAS: Non-traceable Author Statement

F

From FB

GO:0005515

protein binding

FB:FBrf0129865
PMID:10934188[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q8IRY7

F

From FB

GO:0005515

protein binding

FB:FBrf0139798
PMID:11606776[2]

IPI: Inferred from Physical Interaction

FB:FBgn0033402

F

From FB

GO:0005515

protein binding

FB:FBrf0152075
PMID:12433364[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9NHG0

F

From FB

GO:0005737

cytoplasm

FB:FBrf0129865
PMID:10934188[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006915

apoptotic process

FB:FBrf0129865
PMID:10934188[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006915

apoptotic process

FB:FBrf0173268
PMID:12938178[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0006952

defense response

FB:FBrf0133282

NAS: Non-traceable Author Statement

P

From FB

GO:0006955

immune response

FB:FBrf0151243
PMID:12123572[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006963

positive regulation of antibacterial peptide biosynthetic process

FB:FBrf0174342
PMID:15032585[6]

TAS: Traceable Author Statement

P

From FB

GO:0007165

signal transduction

FB:FBrf0133282

NAS: Non-traceable Author Statement

P

From FB

GO:0007291

sperm individualization

FB:FBrf0167989
PMID:14737191[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008633

activation of pro-apoptotic gene products

FB:FBrf0129865
PMID:10934188[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0050700

CARD domain binding

FB:FBrf0129865
PMID:10934188[1]

IPI: Inferred from Physical Interaction

FB:FBgn0020381

F

From FB

GO:0050829

defense response to Gram-negative bacterium

FB:FBrf0152075
PMID:12433364[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050829

defense response to Gram-negative bacterium

FB:FBrf0179043
PMID:15199954[8]

TAS: Traceable Author Statement

P

From FB

GO:0050829

defense response to Gram-negative bacterium

FB:FBrf0192958
PMID:17129215[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0030695

P

From FB

GO:0061057

peptidoglycan recognition protein signaling pathway

FB:FBrf0152075
PMID:12433364[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0013983

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Hu S & Yang X (2000) dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD. J Biol Chem 275: 30761-4 PubMed GONUTS page
  2. Horng T & Medzhitov R (2001) Drosophila MyD88 is an adapter in the Toll signaling pathway. Proc Natl Acad Sci U S A 98: 12654-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 Naitza S et al. (2002) The Drosophila immune defense against gram-negative infection requires the death protein dFADD. Immunity 17: 575-81 PubMed GONUTS page
  4. Lawen A (2003) Apoptosis-an introduction. Bioessays 25: 888-96 PubMed GONUTS page
  5. Leulier F et al. (2002) Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults. Curr Biol 12: 996-1000 PubMed GONUTS page
  6. Brennan CA & Anderson KV (2004) Drosophila: the genetics of innate immune recognition and response. Annu Rev Immunol 22: 457-83 PubMed GONUTS page
  7. Huh JR et al. (2004) Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol 2: E15 PubMed GONUTS page
  8. Leclerc V & Reichhart JM (2004) The immune response of Drosophila melanogaster. Immunol Rev 198: 59-71 PubMed GONUTS page
  9. Libert S et al. (2006) Trade-offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFkappaB signaling. Aging Cell 5: 533-43 PubMed GONUTS page
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