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FB:Atf-2

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Atf-2 ( synonyms: ATF-2, ATF2, CG12850, CG30420, CG3749, dATF-2, dATF2 )
Protein Name(s) Activating transcription factor-2,
External Links
FB FBgn0050420

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

FB:FBrf0188065
PMID:15788564[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

FB:FBrf0201502
PMID:17314398[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0002385

mucosal immune response

FB:FBrf0208708
PMID:19668222[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0005634

nucleus

FB:FBrf0201502
PMID:17314398[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005701

polytene chromosome chromocenter

FB:FBrf0214019
PMID:21703449[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005704

polytene chromosome band

FB:FBrf0214019
PMID:21703449[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0009651

response to salt stress

FB:FBrf0188065
PMID:15788564[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010866

regulation of triglyceride biosynthetic process

FB:FBrf0201502
PMID:17314398[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR009635

C

From FB

GO:0030431

sleep

FB:FBrf0207384
PMID:18694958[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031453

positive regulation of heterochromatin assembly

FB:FBrf0214019
PMID:21703449[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031618

nuclear centromeric heterochromatin

FB:FBrf0214019
PMID:21703449[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0034605

cellular response to heat

FB:FBrf0214019
PMID:21703449[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0152056
PMID:12176927[6]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0188065
PMID:15788564[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0188065
PMID:15788564[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0188065
PMID:15788564[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0201502
PMID:17314398[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0051403

stress-activated MAPK cascade

FB:FBrf0188065
PMID:15788564[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0070829

heterochromatin maintenance

FB:FBrf0214019
PMID:21703449[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0071470

cellular response to osmotic stress

FB:FBrf0188065
PMID:15788564[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0071470

cellular response to osmotic stress

FB:FBrf0214019
PMID:21703449[4]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Sano Y et al. (2005) Drosophila activating transcription factor-2 is involved in stress response via activation by p38, but not c-Jun NH(2)-terminal kinase. Mol Biol Cell 16: 2934-46 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Okamura T et al. (2007) ATF-2 regulates fat metabolism in Drosophila. Mol Biol Cell 18: 1519-29 PubMed GONUTS page
  3. Ha EM et al. (2009) Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut. Nat Immunol 10: 949-57 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Seong KH et al. (2011) Inheritance of stress-induced, ATF-2-dependent epigenetic change. Cell 145: 1049-61 PubMed GONUTS page
  5. Shimizu H et al. (2008) Drosophila ATF-2 regulates sleep and locomotor activity in pacemaker neurons. Mol Cell Biol 28: 6278-89 PubMed GONUTS page
  6. Fassler J et al. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-200 PubMed GONUTS page
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