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FB:Arp66B

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Arp66B ( synonyms: ARP3, AcTr66B, Actin-related protein, Actr66B, Arp2/3, Arp3, CG7558, actin-related protein-3, anon-WO0172774.138, arp3, arp66B, arp66b, schwachling )
Protein Name(s) Actin-related protein 66B,
External Links
FB FBgn0262716

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000902

cell morphogenesis

FB:FBrf0212211
PMID:21041442[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003779

actin binding

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0003826

F

From FB

GO:0005200

structural constituent of cytoskeleton

FB:FBrf0132100
PMID:10908588[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015623

F

From FB

GO:0005884

actin filament

FB:FBrf0076870
PMID:8064864[3]

ISS: Inferred from Sequence or Structural Similarity

EMBL:M81068

C

From FB

GO:0005885

Arp2/3 protein complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0003826

C

From FB

GO:0005885

Arp2/3 protein complex

FB:FBrf0115129

NAS: Non-traceable Author Statement

C

From FB

GO:0005885

Arp2/3 protein complex

FB:FBrf0132100
PMID:10908588[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005885

Arp2/3 protein complex

FB:FBrf0179496
PMID:15196561[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007010

cytoskeleton organization

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0003826

P

From FB

GO:0007010

cytoskeleton organization

FB:FBrf0132100
PMID:10908588[2]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007303

cytoplasmic transport, nurse cell to oocyte

FB:FBrf0144947
PMID:11854308[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007413

axonal fasciculation

FB:FBrf0144948
PMID:11854309[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007520

myoblast fusion

FB:FBrf0201000
PMID:18003739[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007520

myoblast fusion

FB:FBrf0204821
PMID:18388318[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0024273

P

From FB

GO:0007520

myoblast fusion

FB:FBrf0204821
PMID:18388318[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008064

regulation of actin polymerization or depolymerization

FB:FBrf0156686

NAS: Non-traceable Author Statement

P

From FB

GO:0008335

female germline ring canal stabilization

FB:FBrf0144947
PMID:11854308[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015629

actin cytoskeleton

FB:FBrf0156686

NAS: Non-traceable Author Statement

C

From FB

GO:0030027

lamellipodium

FB:FBrf0191917
PMID:17331727[10]

IDA: Inferred from Direct Assay

C

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0201000
PMID:18003739[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030037

actin filament reorganization involved in cell cycle

FB:FBrf0146941
PMID:12007413[11]

IPI: Inferred from Physical Interaction

FB:FBgn0001961

P

From FB

GO:0030589

pseudocleavage involved in syncytial blastoderm formation

FB:FBrf0146941
PMID:12007413[11]

IPI: Inferred from Physical Interaction

FB:FBgn0001961

P

From FB

GO:0030833

regulation of actin filament polymerization

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015623

P

From FB

GO:0051491

positive regulation of filopodium assembly

FB:FBrf0213367
PMID:21464901[12]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. D'Ambrosio MV & Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191: 471-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  3. Fyrberg C et al. (1994) Genes encoding actin-related proteins of Drosophila melanogaster. J Mol Biol 241: 498-503 PubMed GONUTS page
  4. Vartiainen MK & Machesky LM (2004) The WASP-Arp2/3 pathway: genetic insights. Curr Opin Cell Biol 16: 174-81 PubMed GONUTS page
  5. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
  6. 6.0 6.1 Hudson AM & Cooley L (2002) A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex. J Cell Biol 156: 677-87 PubMed GONUTS page
  7. Zallen JA et al. (2002) SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila. J Cell Biol 156: 689-701 PubMed GONUTS page
  8. 8.0 8.1 Richardson BE et al. (2007) SCAR/WAVE and Arp2/3 are crucial for cytoskeletal remodeling at the site of myoblast fusion. Development 134: 4357-67 PubMed GONUTS page
  9. 9.0 9.1 Berger S et al. (2008) WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion. J Cell Sci 121: 1303-13 PubMed GONUTS page
  10. Iwasa JH & Mullins RD (2007) Spatial and temporal relationships between actin-filament nucleation, capping, and disassembly. Curr Biol 17: 395-406 PubMed GONUTS page
  11. 11.0 11.1 Stevenson V et al. (2002) Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos. Curr Biol 12: 705-11 PubMed GONUTS page
  12. Gonçalves-Pimentel C et al. (2011) Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model. PLoS One 6: e18340 PubMed GONUTS page
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