FB:Appl

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Appl ( synonyms: APP, APP-like, APPL, Abeta, BcDNA:GH04413, CG7727, EG:65F1.5, amyloid precursor protein, amyloid precursor protein-like, appl, beta-amyloid-protein-precursor-like )
Protein Name(s) beta amyloid protein precursor-like,
External Links
FB FBgn0000108

Annotations

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0005515

protein binding

FB:FBrf0149603
PMID:11912189[1]

IPI: Inferred from Physical Interaction

FB:FBgn0040281

F

From FB

GO:0005515

protein binding

FB:FBrf0187897
PMID:15976083[2]

IPI: Inferred from Physical Interaction

FB:FBgn0000635

F

From FB

GO:0005576

extracellular region

FB:FBrf0052404
PMID:2125311[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0052404
PMID:2125311[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0123599

NAS: Non-traceable Author Statement

C

From FB

GO:0007399

nervous system development

FB:FBrf0123599

NAS: Non-traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0180199
PMID:15385958[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008154
InterPro:IPR011178
InterPro:IPR015849

C

From FB

GO:0048678

response to axon injury

FB:FBrf0187512
PMID:16052209[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048812

neuron projection morphogenesis

FB:FBrf0187512
PMID:16052209[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050808

synapse organization

FB:FBrf0187897
PMID:15976083[2]

IMP: Inferred from Mutant Phenotype

P

From FB


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Notes

References

See Help:References for how to manage references in GONUTS.
  1. Taru H et al. (2002) Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J Biol Chem 277: 20070-8 PubMed GONUTS page
  2. 2.0 2.1 Ashley J et al. (2005) Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint. J Neurosci 25: 5943-55 PubMed GONUTS page
  3. 3.0 3.1 Luo LQ et al. (1990) Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor. J Neurosci 10: 3849-61 PubMed GONUTS page
  4. Merdes G et al. (2004) Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila. EMBO J 23: 4082-95 PubMed GONUTS page
  5. 5.0 5.1 Leyssen M et al. (2005) Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain. EMBO J 24: 2944-55 PubMed GONUTS page
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