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FB:Apc
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Apc ( synonyms: APC, APC1, Adenomatous Polyposis Coli, Adenomatous Polyposis Coli protein, Adenomatous polyposis coli 1, Apc1, CG1451, D-APC, D-APC1, DAPC, Dm APC1, adenomatous polyposis coli, adenomatous polyposis coli 1, apc, apc 1, apc1, d-APC, dAPC, dAPC1, dApc ) | |
| Protein Name(s) | APC-like, | |
| External Links | ||
| FB | FBgn0015589 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
FB:FBrf0102882 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0151886 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0006886 |
intracellular protein transport |
FB:FBrf0216511 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007017 |
microtubule-based process |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007405 |
neuroblast proliferation |
FB:FBrf0151885 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0007411 |
axon guidance |
FB:FBrf0200173 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0007420 |
brain development |
FB:FBrf0151885 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0007447 |
imaginal disc pattern formation |
FB:FBrf0151886 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0008013 |
beta-catenin binding |
FB:FBrf0091073 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0008017 |
microtubule binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008258 |
head involution |
FB:FBrf0151886 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0016337 |
cell-cell adhesion |
FB:FBrf0200173 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0021550 |
medulla oblongata development |
FB:FBrf0200173 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0030111 |
regulation of Wnt receptor signaling pathway |
FB:FBrf0146980 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0030111 |
regulation of Wnt receptor signaling pathway |
FB:FBrf0151886 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
FB:FBrf0102882 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000117 |
P |
From FB |
||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
FB:FBrf0200173 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0030424 |
axon |
FB:FBrf0151885 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030720 |
oocyte localization involved in germarium-derived egg chamber formation |
FB:FBrf0145163 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0030951 |
establishment or maintenance of microtubule cytoskeleton polarity |
FB:FBrf0212550 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035293 |
chitin-based larval cuticle pattern formation |
FB:FBrf0151886 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026598 |
P |
From FB |
||
| GO:0045177 |
apical part of cell |
FB:FBrf0102882 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0046673 |
negative regulation of compound eye retinal cell programmed cell death |
FB:FBrf0102882 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ahmed Y et al. (1998) Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Cell 93: 1171-82 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Akong K et al. (2002) Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. Dev Biol 250: 91-100 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ Henthorn KS et al. (2011) A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell 22: 4038-46 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Akong K et al. (2002) Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Dev Biol 250: 71-90 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Hayden MA et al. (2007) Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Dev Biol 305: 358-76 PubMed GONUTS page
- ↑ Hayashi S et al. (1997) A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo. Proc Natl Acad Sci U S A 94: 242-7 PubMed GONUTS page
- ↑ Ahmed Y et al. (2002) Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. Development 129: 1751-62 PubMed GONUTS page
- ↑ Hamada F & Bienz M (2002) A Drosophila APC tumour suppressor homologue functions in cellular adhesion. Nat Cell Biol 4: 208-13 PubMed GONUTS page
- ↑ Mattie FJ et al. (2010) Directed microtubule growth, +TIPs, and kinesin-2 are required for uniform microtubule polarity in dendrites. Curr Biol 20: 2169-77 PubMed GONUTS page
