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FB:Alk

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Alk ( synonyms: ALK, Anaplastic Lymphoma Kinase, Anaplastic lymphoma kinase, CG8250, DAlk, DAlk53, anaplastic lymphoma kinase, dALK, mili )
Protein Name(s) Alk,
External Links
FB FBgn0040505

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000186

activation of MAPKK activity

FB:FBrf0162095
PMID:12855999[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0004714

transmembrane receptor protein tyrosine kinase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:103305

F

From FB

GO:0004716

receptor signaling protein tyrosine kinase activity

FB:FBrf0125642

NAS: Non-traceable Author Statement

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002011
InterPro:IPR017441

F

From FB

GO:0005886

plasma membrane

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:103305

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002011

P

From FB

GO:0007411

axon guidance

FB:FBrf0192674
PMID:17350579[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007498

mesoderm development

FB:FBrf0192674
PMID:17350579[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007522

visceral muscle development

FB:FBrf0167923
PMID:14523447[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0040008

regulation of growth

FB:FBrf0216258
PMID:21949657[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042051

compound eye photoreceptor development

FB:FBrf0192674
PMID:17350579[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045610

regulation of hemocyte differentiation

FB:FBrf0180639
PMID:15381778[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045792

negative regulation of cell size

FB:FBrf0216258
PMID:21949657[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048565

digestive tract development

FB:FBrf0162095
PMID:12855999[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0070374

positive regulation of ERK1 and ERK2 cascade

FB:FBrf0216258
PMID:21949657[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0090328

regulation of olfactory learning

FB:FBrf0216258
PMID:21949657[5]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lorén CE et al. (2003) A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster. EMBO Rep 4: 781-6 PubMed GONUTS page
  2. 2.0 2.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 Bazigou E et al. (2007) Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. Cell 128: 961-75 PubMed GONUTS page
  4. Englund C et al. (2003) Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion. Nature 425: 512-6 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Gouzi JY et al. (2011) The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning. PLoS Genet 7: e1002281 PubMed GONUTS page
  6. Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page
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