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FB:Adh

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Adh ( synonyms: ADH, Adh3, BG:DS01486.8, CG32954, CG3481, DmADH, Dreg-1, Drosophila Rhythmically expressed gene 1, Reg-1, T16, adh, alcohol dehydrogenase, alcohol dehyrdrogenase, alcoholdehydrogenase, dADH )
Protein Name(s) Alcohol dehydrogenase,
External Links
FB FBgn0000055

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

From FB

GO:0004022

alcohol dehydrogenase (NAD) activity

FB:FBrf0037533
PMID:6807351[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0004022

alcohol dehydrogenase (NAD) activity

FB:FBrf0039416

IDA: Inferred from Direct Assay

F

From FB

GO:0004022

alcohol dehydrogenase (NAD) activity

FB:FBrf0056371

IDA: Inferred from Direct Assay

F

From FB

GO:0004022

alcohol dehydrogenase (NAD) activity

FB:FBrf0057827
PMID:8461298[2]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0004022

alcohol dehydrogenase (NAD) activity

FB:FBrf0112152
PMID:10471707[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0004022

alcohol dehydrogenase (NAD) activity

FB:FBrf0167996
PMID:12972637[4]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0005811

lipid particle

FB:FBrf0192399
PMID:16543254[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005811

lipid particle

FB:FBrf0200342

IDA: Inferred from Direct Assay

C

From FB

GO:0005829

cytosol

FB:FBrf0058677
PMID:8353517[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0006066

alcohol metabolic process

FB:FBrf0037533
PMID:6807351[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0006067

ethanol metabolic process

FB:FBrf0056371

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006069

ethanol oxidation

FB:FBrf0039416

IDA: Inferred from Direct Assay

P

From FB

GO:0006117

acetaldehyde metabolic process

FB:FBrf0039416

IDA: Inferred from Direct Assay

P

From FB

GO:0006117

acetaldehyde metabolic process

FB:FBrf0056371

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008774

acetaldehyde dehydrogenase (acetylating) activity

FB:FBrf0039416

IDA: Inferred from Direct Assay

F

From FB

GO:0008774

acetaldehyde dehydrogenase (acetylating) activity

FB:FBrf0056371

IDA: Inferred from Direct Assay

F

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0180459
PMID:15581900[8]

IPI: Inferred from Physical Interaction

FB:FBgn0000055

F

From FB

GO:0043234

protein complex

FB:FBrf0180459
PMID:15581900[8]

IPI: Inferred from Physical Interaction

FB:FBgn0000055

C

From FB

GO:0046164

alcohol catabolic process

FB:FBrf0057827
PMID:8461298[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048149

behavioral response to ethanol

FB:FBrf0155893
PMID:12486199[9]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Winberg JO et al. (1982) Alcohol dehydrogenase from the fruitfly Drosophila melanogaster. Substrate specificity of the alleloenzymes AdhS and AdhUF. Biochim Biophys Acta 704: 7-16 PubMed GONUTS page
  2. 2.0 2.1 Chen Z et al. (1993) Site-specific mutagenesis of Drosophila alcohol dehydrogenase: evidence for involvement of tyrosine-152 and lysine-156 in catalysis. Biochemistry 32: 3342-6 PubMed GONUTS page
  3. Ashburner M et al. (1999) An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics 153: 179-219 PubMed GONUTS page
  4. Chen Y & Stephan W (2003) Compensatory evolution of a precursor messenger RNA secondary structure in the Drosophila melanogaster Adh gene. Proc Natl Acad Sci U S A 100: 11499-504 PubMed GONUTS page
  5. Beller M et al. (2006) Characterization of the Drosophila lipid droplet subproteome. Mol Cell Proteomics 5: 1082-94 PubMed GONUTS page
  6. Leal JF & Barbancho M (1993) Aldehyde dehydrogenase (ALDH) activity in Drosophila melanogaster adults: evidence for cytosolic localization. Insect Biochem Mol Biol 23: 543-7 PubMed GONUTS page
  7. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  8. 8.0 8.1 Benach J et al. (2005) Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis. J Mol Biol 345: 579-98 PubMed GONUTS page
  9. Wolf FW et al. (2002) High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila. J Neurosci 22: 11035-44 PubMed GONUTS page
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