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FB:Acsl

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Acsl ( synonyms: 7447, CG8732, FACS, FCS, Fatty acyl CoA synthetase, Fatty acyl-CoA synthetase, Long-chain acyl-CoA synthetase, anon-WO0172774.173, dAcsl, dFAC, fatty acyl coenzyme A (CoA) synthetase, fatty acyl-CoA synthetase, l(2)05847, l(2)44DEa, l(2)7447, l(2)SH0465, l(2)SH2 0465, l(2)k05304, lethal (2) 44DEa, lethal (2) SH0465, long-chain acyl-CoA synthetase )
Protein Name(s) Acyl-CoA synthetase long-chain,
External Links
FB FBgn0263120

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004467

long-chain fatty acid-CoA ligase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O35547

F

From FB

GO:0005737

cytoplasm

FB:FBrf0209077
PMID:19617635[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0213522
PMID:21385576[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005783

endoplasmic reticulum

FB:FBrf0209077
PMID:19617635[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005811

lipid particle

FB:FBrf0192764
PMID:16979555[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0007268

synaptic transmission

FB:FBrf0212968
PMID:21307243[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007399

nervous system development

FB:FBrf0209077
PMID:19617635[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0209077
PMID:19617635[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008152

metabolic process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000873

P

From FB

GO:0010890

positive regulation of sequestering of triglyceride

FB:FBrf0209077
PMID:19617635[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035282

segmentation

FB:FBrf0213522
PMID:21385576[2]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Zhang Y et al. (2009) Analyses of mental dysfunction-related ACSl4 in Drosophila reveal its requirement for Dpp/BMP production and visual wiring in the brain. Hum Mol Genet 18: 3894-905 PubMed GONUTS page
  2. 2.0 2.1 Zhang Y et al. (2011) Drosophila long-chain acyl-CoA synthetase acts like a gap gene in embryonic segmentation. Dev Biol 353: 259-65 PubMed GONUTS page
  3. Cermelli S et al. (2006) The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr Biol 16: 1783-95 PubMed GONUTS page
  4. Liu Z et al. (2011) Drosophila Acyl-CoA synthetase long-chain family member 4 regulates axonal transport of synaptic vesicles and is required for synaptic development and transmission. J Neurosci 31: 2052-63 PubMed GONUTS page


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