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FB:Acf1

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Acf1 ( synonyms: ACF, ACF/CHRAC, ACF1, ATP-utilizing chromatin assembly and remodeling factor, Acf, Acf-1, CAF, CG1966, CHRAC, CHRAC-175, Chromatin Accessibility Complex, acf1, dACF, dCHRAC, p170/p185 )
Protein Name(s) ATP-dependent chromatin assembly factor large subunit,
External Links
FB FBgn0027620

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

FB:FBrf0159374
PMID:12192034[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0173283
PMID:14635254[2]

TAS: Traceable Author Statement

F

From FB

GO:0005515

protein binding

FB:FBrf0159374
PMID:12192034[1]

IPI: Inferred from Physical Interaction

FB:FBgn0011604

F

From FB

GO:0005678

chromatin assembly complex

FB:FBrf0105495

NAS: Non-traceable Author Statement

C

From FB

GO:0005678

chromatin assembly complex

FB:FBrf0116451

NAS: Non-traceable Author Statement

C

From FB

GO:0006333

chromatin assembly or disassembly

FB:FBrf0105495

NAS: Non-traceable Author Statement

P

From FB

GO:0006333

chromatin assembly or disassembly

FB:FBrf0116451

NAS: Non-traceable Author Statement

P

From FB

GO:0006333

chromatin assembly or disassembly

FB:FBrf0173283
PMID:14635254[2]

TAS: Traceable Author Statement

P

From FB

GO:0006334

nucleosome assembly

FB:FBrf0095281
PMID:9230310[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0006334

nucleosome assembly

FB:FBrf0109981
PMID:10385622[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0095281
PMID:9230310[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0007399

nervous system development

FB:FBrf0200690
PMID:17376868[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007517

muscle organ development

FB:FBrf0190556
PMID:16547170[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001965

F

From FB

GO:0008544

epidermis development

FB:FBrf0190556
PMID:16547170[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008623

chromatin accessibility complex

FB:FBrf0127884

NAS: Non-traceable Author Statement

C

From FB

GO:0008623

chromatin accessibility complex

FB:FBrf0138380
PMID:11447119[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0016584

nucleosome positioning

FB:FBrf0095281
PMID:9230310[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0016590

ACF complex

FB:FBrf0095281
PMID:9230310[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0016590

ACF complex

FB:FBrf0109981
PMID:10385622[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0016590

ACF complex

FB:FBrf0109981
PMID:10385622[4]

IPI: Inferred from Physical Interaction

FB:FBgn0011604

C

From FB

GO:0031497

chromatin assembly

FB:FBrf0159374
PMID:12192034[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0138380
PMID:11447119[7]

IDA: Inferred from Direct Assay

P

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0173283
PMID:14635254[2]

TAS: Traceable Author Statement

P

From FB

GO:0043462

regulation of ATPase activity

FB:FBrf0159374
PMID:12192034[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0206995
PMID:18786525[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048666

neuron development

FB:FBrf0190556
PMID:16547170[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[6]

IMP: Inferred from Mutant Phenotype

P

From FB

NOT

GO:0004402

histone acetyltransferase activity

FB:FBrf0109981
PMID:10385622[4]

IDA: Inferred from Direct Assay

F

From FB

NOT

GO:0016589

NURF complex

FB:FBrf0109981
PMID:10385622[4]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Fyodorov DV & Kadonaga JT (2002) Binding of Acf1 to DNA involves a WAC motif and is important for ACF-mediated chromatin assembly. Mol Cell Biol 22: 6344-53 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lusser A & Kadonaga JT (2003) Chromatin remodeling by ATP-dependent molecular machines. Bioessays 25: 1192-200 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Ito T et al. (1997) ACF, an ISWI-containing and ATP-utilizing chromatin assembly and remodeling factor. Cell 90: 145-55 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Ito T et al. (1999) ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly. Genes Dev 13: 1529-39 PubMed GONUTS page
  5. Koizumi K et al. (2007) RNA interference screen to identify genes required for Drosophila embryonic nervous system development. Proc Natl Acad Sci U S A 104: 5626-31 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
  7. 7.0 7.1 Eberharter A et al. (2001) Acf1, the largest subunit of CHRAC, regulates ISWI-induced nucleosome remodelling. EMBO J 20: 3781-8 PubMed GONUTS page
  8. Liu YI et al. (2008) The chromatin remodelers ISWI and ACF1 directly repress Wingless transcriptional targets. Dev Biol 323: 41-52 PubMed GONUTS page
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