FB:Abd-B

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Abd-B ( synonyms: ABD-B, ABDB, Abd B, Abd-b, Abd0B, AbdB, AbdB(CA)((26)), AbdB-I, AbdB-II, Abdominal-B, AbdominalB, AdbB, BX-C, CG10291, CG11648, DROABDB, Droabdb, FAB, Fab-7, Fab-8, Fab7, IAB 5, IAB5, IAB8, Iab-7, MCP, Male chauvinist pigmentation, Mc, Mcp, Microcephalus, Miscadastral pigmentation, Sab, Superabdominal, Tab, Transabdominal, Uab-5(Sab), abd-B, abdB, bex, iab, iab-5, iab-6, iab-7, iab-8, iab-8,9, iab5, iab6, iab7, iab8, iab8.9, iab9, infra-abdominal 5, infra-abdominal 6, infra-abdominal 7, infra-abdominal 8, infra-abdominal 9, infraabdominal, infraabdominal-8.9, l(3)89Ed, pH189, tuh-3, twig )
Protein Name(s) Abdominal B,
External Links
FB FBgn0000015

Annotations

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0003700

transcription factor activity

FB:FBrf0193256
PMID:16814723[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003704

specific RNA polymerase II transcription factor activity

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0003704

specific RNA polymerase II transcription factor activity

FB:FBrf0123479

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0123479

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001356
InterPro:IPR017970

P

From FB

GO:0007280

pole cell migration

FB:FBrf0102832
PMID:9637912[2]

TAS: Traceable Author Statement

P

From FB

GO:0007385

specification of segmental identity, abdomen

FB:FBrf0137175
PMID:11494318[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0007385

specification of segmental identity, abdomen

FB:FBrf0193405
PMID:16818450[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007385

specification of segmental identity, abdomen

FB:FBrf0194816
PMID:16971094[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0194228
PMID:17113384[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007431

salivary gland development

FB:FBrf0168046
PMID:14624839[7]

NAS: Non-traceable Author Statement

P

From FB

GO:0007484

imaginal disc-derived genitalia development

FB:FBrf0155450
PMID:12386929[8]

TAS: Traceable Author Statement

P

From FB

GO:0007486

imaginal disc-derived female genitalia development

FB:FBrf0194816
PMID:16971094[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007494

midgut development

FB:FBrf0111439
PMID:10512197[9]

TAS: Traceable Author Statement

P

From FB

GO:0007506

gonadal mesoderm development

FB:FBrf0100771
PMID:9435287[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007506

gonadal mesoderm development

FB:FBrf0180482
PMID:15454263[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007507

heart development

FB:FBrf0160748
PMID:12837580[12]

NAS: Non-traceable Author Statement

P

From FB

GO:0007548

sex differentiation

FB:FBrf0156093
PMID:12350340[13]

NAS: Non-traceable Author Statement

P

From FB

GO:0008354

germ cell migration

FB:FBrf0100771
PMID:9435287[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008354

germ cell migration

FB:FBrf0107500
PMID:9988212[14]

TAS: Traceable Author Statement

P

From FB

GO:0008406

gonad development

FB:FBrf0078100

NAS: Non-traceable Author Statement

P

From FB

GO:0008584

male gonad development

FB:FBrf0180482
PMID:15454263[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008595

determination of anterior/posterior axis, embryo

FB:FBrf0123479

NAS: Non-traceable Author Statement

P

From FB

GO:0009997

negative regulation of cardioblast cell fate specification

FB:FBrf0151890
PMID:12435360[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030539

male genitalia development

FB:FBrf0190286
PMID:16319117[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030540

female genitalia development

FB:FBrf0190286
PMID:16319117[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035215

genital disc development

FB:FBrf0137175
PMID:11494318[3]

TAS: Traceable Author Statement

P

From FB

GO:0035224

genital disc anterior/posterior pattern formation

FB:FBrf0088118
PMID:8798147[17]

IEP: Inferred from Expression Pattern

P

From FB

GO:0035225

determination of genital disc primordium

FB:FBrf0187379
PMID:15893978[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035261

external genitalia morphogenesis

FB:FBrf0190286
PMID:16319117[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035263

genital disc sexually dimorphic development

FB:FBrf0187379
PMID:15893978[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035277

spiracle morphogenesis, open tracheal system

FB:FBrf0111388
PMID:10491268[19]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001356
InterPro:IPR017970

F

From FB

GO:0045705

negative regulation of salivary gland boundary specification

FB:FBrf0139594
PMID:11598957[20]

TAS: Traceable Author Statement

P

From FB

GO:0045705

negative regulation of salivary gland boundary specification

FB:FBrf0159337
PMID:12742168[21]

TAS: Traceable Author Statement

P

From FB

GO:0045843

negative regulation of striated muscle tissue development

FB:FBrf0151932
PMID:12397110[22]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048066

pigmentation during development

FB:FBrf0155986
PMID:12459721[23]

NAS: Non-traceable Author Statement

P

From FB

GO:0048071

sex-specific pigmentation

FB:FBrf0141067

TAS: Traceable Author Statement

P

From FB

GO:0048071

sex-specific pigmentation

FB:FBrf0162298
PMID:12957543[24]

TAS: Traceable Author Statement

P

From FB

GO:0048087

positive regulation of pigmentation during development

FB:FBrf0156093
PMID:12350340[13]

NAS: Non-traceable Author Statement

P

From FB


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Notes

References

See Help:References for how to manage references in GONUTS.
  1. Jeong S et al. (2006) Regulation of body pigmentation by the Abdominal-B Hox protein and its gain and loss in Drosophila evolution. Cell 125: 1387-99 PubMed GONUTS page
  2. Howard K (1998) Organogenesis: Drosophila goes gonadal. Curr Biol 8: R415-7 PubMed GONUTS page
  3. 3.0 3.1 Sanchez L & Guerrero I (2001) The development of the Drosophila genital disc. Bioessays 23: 698-707 PubMed GONUTS page
  4. Mihaly J et al. (2006) Dissecting the regulatory landscape of the Abd-B gene of the bithorax complex. Development 133: 2983-93 PubMed GONUTS page
  5. 5.0 5.1 de Navas L et al. (2006) A simple and efficient method to identify replacements of P-lacZ by P-Gal4 lines allows obtaining Gal4 insertions in the bithorax complex of Drosophila. Mech Dev 123: 860-7 PubMed GONUTS page
  6. Lovegrove B et al. (2006) Coordinated control of cell adhesion, polarity, and cytoskeleton underlies Hox-induced organogenesis in Drosophila. Curr Biol 16: 2206-16 PubMed GONUTS page
  7. Nelson WJ (2003) Tube morphogenesis: closure, but many openings remain. Trends Cell Biol 13: 615-21 PubMed GONUTS page
  8. Damen WG (2002) fushi tarazu: a Hox gene changes its role. Bioessays 24: 992-5 PubMed GONUTS page
  9. Murakami R et al. (1999) Developmental genetics of the Drosophila gut: specification of primordia, subdivision and overt-differentiation. Cell Mol Biol (Noisy-le-grand) 45: 661-76 PubMed GONUTS page
  10. 10.0 10.1 Moore LA et al. (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-78 PubMed GONUTS page
  11. 11.0 11.1 DeFalco T et al. (2004) Abdominal-B is essential for proper sexually dimorphic development of the Drosophila gonad. Mech Dev 121: 1323-33 PubMed GONUTS page
  12. Lo PC & Frasch M (2003) Establishing A-P polarity in the embryonic heart tube: a conserved function of Hox genes in Drosophila and vertebrates? Trends Cardiovasc Med 13: 182-7 PubMed GONUTS page
  13. 13.0 13.1 Christiansen AE et al. (2002) Sex comes in from the cold: the integration of sex and pattern. Trends Genet 18: 510-6 PubMed GONUTS page
  14. Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
  15. Lo PC et al. (2002) Homeotic genes autonomously specify the anteroposterior subdivision of the Drosophila dorsal vessel into aorta and heart. Dev Biol 251: 307-19 PubMed GONUTS page
  16. 16.0 16.1 16.2 Foronda D et al. (2006) Requirement of Abdominal-A and Abdominal-B in the developing genitalia of Drosophila breaks the posterior downregulation rule. Development 133: 117-27 PubMed GONUTS page
  17. Freeland DE & Kuhn DT (1996) Expression patterns of developmental genes reveal segment and parasegment organization of D. melanogaster genital discs. Mech Dev 56: 61-72 PubMed GONUTS page
  18. 18.0 18.1 Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
  19. Hu N & Castelli-Gair J (1999) Study of the posterior spiracles of Drosophila as a model to understand the genetic and cellular mechanisms controlling morphogenesis. Dev Biol 214: 197-210 PubMed GONUTS page
  20. Bradley PL et al. (2001) Organ formation in Drosophila: specification and morphogenesis of the salivary gland. Bioessays 23: 901-11 PubMed GONUTS page
  21. Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
  22. Lovato TL et al. (2002) The Hox gene abdominal-A specifies heart cell fate in the Drosophila dorsal vessel. Development 129: 5019-27 PubMed GONUTS page
  23. Simpson P (2002) Evolution of development in closely related species of flies and worms. Nat Rev Genet 3: 907-17 PubMed GONUTS page
  24. Wittkopp PJ et al. (2003) Evolution in black and white: genetic control of pigment patterns in Drosophila. Trends Genet 19: 495-504 PubMed GONUTS page
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