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FB:18w
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | 18w ( synonyms: 18 Wheeler, 18-Wheeler, 18-wheeler, 18W, 18Wheeler, 18wheeler, CG8896, CT25100, Toll like receptor, Toll-2, l(2)00053, tlr, toll, toll receptor, wheeler ) | |
| Protein Name(s) | 18 wheeler, | |
| External Links | ||
| FB | FBgn0004364 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004888 |
transmembrane signaling receptor activity |
FB:FBrf0073029 |
ISS: Inferred from Sequence or Structural Similarity |
FB:FBgn0262473 |
F |
From FB |
||
| GO:0004888 |
transmembrane signaling receptor activity |
FB:FBrf0133282 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004888 |
transmembrane signaling receptor activity |
FB:FBrf0141274 |
ISS: Inferred from Sequence or Structural Similarity |
FB:FBgn0034476 |
F |
From FB |
||
| GO:0005624 |
membrane fraction |
FB:FBrf0073029 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0099002 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0073029 |
ISS: Inferred from Sequence or Structural Similarity |
FB:FBgn0262473 |
C |
From FB |
||
| GO:0005886 |
plasma membrane |
FB:FBrf0099002 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0127230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0099002 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0073029 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0133282 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007275 |
multicellular organismal development |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009653 |
anatomical structure morphogenesis |
FB:FBrf0073029 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0133282 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0019731 |
antibacterial humoral response |
FB:FBrf0099002 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019731 |
antibacterial humoral response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0019731 |
antibacterial humoral response |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031224 |
intrinsic to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0045087 |
innate immune response |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0048598 |
embryonic morphogenesis |
FB:FBrf0127230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
|
NOT |
GO:0019730 |
antimicrobial humoral response |
FB:FBrf0151288 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Eldon E et al. (1994) The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development 120: 885-99 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Williams MJ et al. (1997) The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J 16: 6120-30 PubMed GONUTS page
- ↑ 3.0 3.1 Meister M et al. (2000) The antimicrobial host defense of Drosophila. Curr Top Microbiol Immunol 248: 17-36 PubMed GONUTS page
- ↑ 4.0 4.1 Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
- ↑ Ligoxygakis P et al. (2002) Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila. EMBO Rep 3: 666-73 PubMed GONUTS page
