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FB:14-3-3epsilon
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | 14-3-3epsilon ( synonyms: 14-3-3, 14-3-3 epsilon, 14-3-3&epsilon, 14-3-3-e, 14-3-3-epsilon, 14-3-30epsilon, 14-3-3EPSILON, 14-3-3e, 14-3-3omicron, 1433epsilon, 143E_DROME, CG31196, CT24092, D14-3-3e, D14-3-3epsilon, EK3-5, PAR-5, PAR5, Par-5, SR3-9, Su(Raf)3B, Suppressor of Ras85D 3-9, Tyrosine-3-monooxygenase, anon-WO0172774.141, anon-WO02059370.52, d14-3-3epsilon, l(3)j2B10, par-5 ) | |
| Protein Name(s) | 14-3-3epsilon, | |
| External Links | ||
| FB | FBgn0020238 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000077 |
DNA damage checkpoint |
FB:FBrf0127025 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000077 |
DNA damage checkpoint |
FB:FBrf0130073 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000077 |
DNA damage checkpoint |
FB:FBrf0139721 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0139721 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005694 |
chromosome |
FB:FBrf0139721 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0139721 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0204649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007088 |
regulation of mitosis |
FB:FBrf0139721 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007093 |
mitotic cell cycle checkpoint |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261530 |
P |
From FB |
||
| GO:0007265 |
Ras protein signal transduction |
FB:FBrf0113721 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007265 |
Ras protein signal transduction |
FB:FBrf0124174 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0151902 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007444 |
imaginal disc development |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008103 |
oocyte microtubule cytoskeleton polarization |
FB:FBrf0151902 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0207166 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008426 |
protein kinase C inhibitor activity |
FB:FBrf0113721 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0009314 |
response to radiation |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009411 |
response to UV |
FB:FBrf0207166 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019904 |
protein domain specific binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0040008 |
regulation of growth |
FB:FBrf0207166 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0038197 |
P |
From FB |
||
| GO:0045172 |
germline ring canal |
FB:FBrf0151902 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045927 |
positive regulation of growth |
FB:FBrf0207166 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046958 |
nonassociative learning |
FB:FBrf0154848 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0209680 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004907 |
F |
From FB |
||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0202749 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000242 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Brodsky MH et al. (2000) mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development. Genes Dev 14: 666-78 PubMed GONUTS page
- ↑ Sekelsky JJ et al. (2000) DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol 150: F31-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Su TT et al. (2001) Cell cycle roles for two 14-3-3 proteins during Drosophila development. J Cell Sci 114: 3445-54 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Walworth NC (2000) Cell-cycle checkpoint kinases: checking in on the cell cycle. Curr Opin Cell Biol 12: 697-704 PubMed GONUTS page
- ↑ Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Benton R et al. (2002) Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation. Dev Cell 3: 659-71 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Nielsen MD et al. (2008) 14-3-3 Epsilon antagonizes FoxO to control growth, apoptosis and longevity in Drosophila. Aging Cell 7: 688-99 PubMed GONUTS page
- ↑ Messaritou G et al. (2010) Dimerization is essential for 14-3-3zeta stability and function in vivo. J Biol Chem 285: 1692-700 PubMed GONUTS page
- ↑ Bejarano F et al. (2008) A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing. Genetics 178: 307-23 PubMed GONUTS page
