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ENTCL:Q6W9J1
Contents |
| Species (Taxon ID) | Enterobacter cloacae. ([1]) | |
| Gene Name(s) | blaTEM-1 (synonyms: blaTEM) | |
| Protein Name(s) | Beta-lacatamase TEM-1
Beta-lactamase TEM-1 TEM-1 beta-lactamase | |
| External Links | ||
| EMBL | AY302260 EU855787 EU855788 GQ336884 HM131427 | |
| RefSeq | YP_002791371.1 YP_002791681.1 | |
| HSSP | P00807 | |
| ProteinModelPortal | Q6W9J1 | |
| SMR | Q6W9J1 | |
| PRIDE | Q6W9J1 | |
| GeneID | 7752180 7752331 | |
| ProtClustDB | PRK15442 | |
| GO | GO:0008800 GO:0030655 GO:0046677 | |
| InterPro | IPR001466 IPR012338 IPR000871 IPR023650 | |
| Gene3D | G3DSA:3.40.710.10 | |
| Pfam | PF00144 | |
| PRINTS | PR00118 | |
| SUPFAM | SSF56601 | |
| PROSITE | PS00146 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0008800 |
beta-lactamase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016787 |
hydrolase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0030655 |
beta-lactam antibiotic catabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0046677 |
response to antibiotic |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0046677 |
response to antibiotic |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008800 |
beta-lactamase activity |
IMP: Inferred from Mutant Phenotype |
F |
Table one provides natural amino acid substitutions that increased the activity to cleave the amide bond in extended-spectrum cephalosporins and generate inactive products |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Palzkill T & Botstein D (1992) Identification of amino acid substitutions that alter the substrate specificity of TEM-1 beta-lactamase. J Bacteriol 174: 5237-43 PubMed GONUTS page