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ENTCL:Q6W9J1

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Contents

Species (Taxon ID) Enterobacter cloacae. ([1])
Gene Name(s) blaTEM-1 (synonyms: blaTEM)
Protein Name(s) Beta-lacatamase TEM-1

Beta-lactamase TEM-1 TEM-1 beta-lactamase

External Links
EMBL AY302260
EU855787
EU855788
GQ336884
HM131427
RefSeq YP_002791371.1
YP_002791681.1
HSSP P00807
ProteinModelPortal Q6W9J1
SMR Q6W9J1
PRIDE Q6W9J1
GeneID 7752180
7752331
ProtClustDB PRK15442
GO GO:0008800
GO:0030655
GO:0046677
InterPro IPR001466
IPR012338
IPR000871
IPR023650
Gene3D G3DSA:3.40.710.10
Pfam PF00144
PRINTS PR00118
SUPFAM SSF56601
PROSITE PS00146

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0008800

beta-lactamase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000871

F

Seeded From UniProt

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded From UniProt

GO:0030655

beta-lactam antibiotic catabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000871

P

Seeded From UniProt

GO:0046677

response to antibiotic

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000871

P

Seeded From UniProt

GO:0046677

response to antibiotic

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0046

P

Seeded From UniProt

GO:0008800

beta-lactamase activity

PMID:1644749[1]

IMP: Inferred from Mutant Phenotype

F

Table one provides natural amino acid substitutions that increased the activity to cleave the amide bond in extended-spectrum cephalosporins and generate inactive products

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Palzkill T & Botstein D (1992) Identification of amino acid substitutions that alter the substrate specificity of TEM-1 beta-lactamase. J Bacteriol 174: 5237-43 PubMed GONUTS page
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