ECOLI:SRP54

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Species (Taxon ID)	Escherichia coli (strain K12). (taxon:83333)
Gene Name(s)	ffh
Protein Name(s)	Signal recognition particle protein Fifty-four homolog p48
External Links
UniProt Identifier	SRP54_ECOLI
UniProt Accessions	P0AGD7, P07019, P77007, P77008,
EMBL	X01818, U00096, AP009048,
PIR	E65039,
RefSeq	AP_003191.1, NP_417101.1,
PDB	1DUL, 1HQ1, 2J28, 2PXB, 2PXD, 2PXE, 2PXF, 2PXK, 2PXL, 2PXP, 2PXQ, 2PXT, 2PXU, 2PXV, 2XKV, 2XXA, 3LQX,
Pfam	PF00448, PF02881, PF02978,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect
	GO:0048500	signal recognition particle	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004780	C
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F
	GO:0005525	GTP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013822	F
	GO:0000166	nucleotide binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F
	GO:0048500	signal recognition particle	PMID:1701272^[1]	IMP: Inferred from Mutant Phenotype		C
	GO:0008312	7S RNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004125	F
	GO:0005525	GTP binding	PMID:7612669^[2]	IMP: Inferred from Mutant Phenotype		F
	GO:0005525	GTP binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0342	F
	GO:0030529	ribonucleoprotein complex	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0687	C
	GO:0006184	GTP catabolic process	PMID:7612669^[2]	IDA: Inferred from Direct Assay		P
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004780	P
	GO:0005525	GTP binding	PMID:7612669^[2]	IDA: Inferred from Direct Assay		F
	GO:0008312	7S RNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004780	F
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013822	P
	GO:0048500	signal recognition particle	PMID:1331806^[3]	IMP: Inferred from Mutant Phenotype		C
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004125	P
	GO:0000166	nucleotide binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000897	P
	GO:0005525	GTP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000897	F
	GO:0003924	GTPase activity	PMID:7612669^[2]	IDA: Inferred from Direct Assay		F
	GO:0048500	signal recognition particle	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004125	C
	GO:0005786	signal recognition particle, endoplasmic reticulum targeting	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0733	C
	GO:0003924	GTPase activity	PMID:7612669^[2]	IMP: Inferred from Mutant Phenotype		F
	GO:0030529	ribonucleoprotein complex	PMID:1701272^[1]	IDA: Inferred from Direct Assay		C
	GO:0003723	RNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0694	F
	GO:0006612	protein targeting to membrane	PMID:1331806^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0000166	nucleotide binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F
	GO:0000166	nucleotide binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F
	GO:0003723	RNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0694	F
	GO:0003924	GTPase activity	PMID:7612669^[2]	IMP: Inferred from Mutant Phenotype		F
	GO:0005525	GTP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000897	F
	GO:0005525	GTP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013822	F
	GO:0005525	GTP binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0342	F
	GO:0005525	GTP binding	PMID:7612669^[2]	IDA: Inferred from Direct Assay		F
	GO:0005525	GTP binding	PMID:7612669^[2]	IMP: Inferred from Mutant Phenotype		F
	GO:0005786	signal recognition particle, endoplasmic reticulum targeting	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0733	C
	GO:0006184	GTP catabolic process	PMID:7612669^[2]	IMP: Inferred from Mutant Phenotype		P
	GO:0006612	protein targeting to membrane	PMID:1331806^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000897	P
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004125	P
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004780	P
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013822	P
	GO:0008312	7S RNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004125	F
	GO:0008312	7S RNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004780	F
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F
	GO:0030529	ribonucleoprotein complex	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0687	C
	GO:0030529	ribonucleoprotein complex	PMID:1701272^[1]	IDA: Inferred from Direct Assay		C
	GO:0048500	signal recognition particle	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004125	C
	GO:0048500	signal recognition particle	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004780	C
	GO:0048500	signal recognition particle	PMID:1331806^[3]	IMP: Inferred from Mutant Phenotype		C
	GO:0048500	signal recognition particle	PMID:1701272^[1]	IMP: Inferred from Mutant Phenotype		C
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Poritz MA et al. (1990) An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science 250: 1111-7 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 Samuelsson T et al. (1995) The GTPase activity of the Escherichia coli Ffh protein is important for normal growth. Biochim Biophys Acta 1267: 83-91 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Phillips GJ & Silhavy TJ (1992) The E. coli ffh gene is necessary for viability and efficient protein export. Nature 359: 744-6 PubMed GONUTS page

[PMID:1701272-0] 1.0 ^1.1 ^1.2 ^1.3 Poritz MA et al. (1990) An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science 250: 1111-7 PubMed GONUTS page

[PMID:7612669-1] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 Samuelsson T et al. (1995) The GTPase activity of the Escherichia coli Ffh protein is important for normal growth. Biochim Biophys Acta 1267: 83-91 PubMed GONUTS page

[PMID:1331806-2] 3.0 ^3.1 ^3.2 ^3.3 Phillips GJ & Silhavy TJ (1992) The E. coli ffh gene is necessary for viability and efficient protein export. Nature 359: 744-6 PubMed GONUTS page

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ECOLI:SRP54

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