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ECOLI:PTNC

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) manY (synonyms: pel, ptsP)
Protein Name(s) Mannose permease IIC component

EII-P-Man EIIC-Man PTS system mannose-specific EIIC component

External Links
UniProt P69801
EMBL J02699
U00096
AP009048
M36404
PIR A30285
RefSeq NP_416332.1
YP_490079.1
ProteinModelPortal P69801
IntAct P69801
STRING 511145.b1818
TCDB 4.A.6.1.1
PaxDb P69801
EnsemblBacteria AAC74888
BAA15625
GeneID 12930151
946332
KEGG ecj:Y75_p1793
eco:b1818
PATRIC 32118955
EchoBASE EB0563
EcoGene EG10568
eggNOG COG3715
HOGENOM HOG000097554
InParanoid P69801
KO K02795
OMA LSWIHVS
OrthoDB EOG610496
PhylomeDB P69801
BioCyc EcoCyc:MANY-MONOMER
ECOL316407:JW1807-MONOMER
MetaCyc:MANY-MONOMER
PRO PR:P69801
Proteomes UP000000318
UP000000625
Genevestigator P69801
GO GO:0005887
GO:0016020
GO:0022870
GO:0015761
GO:0009401
InterPro IPR004700
PANTHER PTHR32502:SF4
Pfam PF03609
TIGRFAMs TIGR00822
PROSITE PS51106

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005887

integral to plasma membrane

PMID:8774730[1]

ECO:0000255

PMID:7108955[2]


C

Fig. 1A shows the hydropathy plot, indicating this protein is located in the plasma membrane.

complete
CACAO 8776

part_of

GO:0005887

integral component of plasma membrane

PMID:8774730[1]

ECO:0000255

match to sequence model evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

part_of

GO:0016020

membrane

PMID:16858726[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10568
EcoGene:EG10569
PANTHER:PTN000789828

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10568
EcoGene:EG10569
PANTHER:PTN000789828

C

Seeded From UniProt

complete

involved_in

GO:0098708

glucose import across plasma membrane

PMID:5545083[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0022870

protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity

PMID:2951378[6]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0015761

mannose transmembrane transport

PMID:5545083[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

PMID:2951378[6]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:2951378[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15919996[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004700

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004700

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-KW:KW-0997
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0762

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0598

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Huber, F & Erni, B (1996) Membrane topology of the mannose transporter of Escherichia coli K12. Eur. J. Biochem. 239 810-7 PubMed GONUTS page
  2. Kyte, J & Doolittle, RF (1982) A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157 105-32 PubMed GONUTS page
  3. Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
  4. 4.0 4.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  5. 5.0 5.1 Kundig, W & Roseman, S (1971) Sugar transport. II. Characterization of constitutive membrane-bound enzymes II of the Escherichia coli phosphotransferase system. J. Biol. Chem. 246 1407-18 PubMed GONUTS page
  6. 6.0 6.1 6.2 Erni, B et al. (1987) The mannose permease of Escherichia coli consists of three different proteins. Amino acid sequence and function in sugar transport, sugar phosphorylation, and penetration of phage lambda DNA. J. Biol. Chem. 262 5238-47 PubMed GONUTS page
  7. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page