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ECOLI:LPXK

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Contents

Species (Taxon ID) Escherichia coli (strain K12). (taxon:83333)
Gene Name(s) lpxK ( synonyms: ycaH )
Protein Name(s)
  • Tetraacyldisaccharide 4'-kinase
  • Lipid A 4'-kinase
External Links
UniProt Identifier LPXK_ECOLI
UniProt Accessions P27300, P75842, Q9R7Q6,
EMBL Z11796, U00096, AP009048,
PIR B64831,
RefSeq AP_001545.1, NP_415435.1,
Pfam PF02606,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003758

F

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

GO:0008610

lipid biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0444

P

GO:0009029

tetraacyldisaccharide 4'-kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003758

F

GO:0009029

tetraacyldisaccharide 4'-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.130

F

GO:0009245

lipid A biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003758

P

GO:0009245

lipid A biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0441

P

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

GO:0016020

membrane

PMID:9268317[1]

IDA: Inferred from Direct Assay

C

Fig.6, lanes 4&8

complete

GO:0009029

tetraacyldisaccharide 4'-kinase activity

PMID:9268317[1]

IDA: Inferred from Direct Assay

F

Fig.5

complete

GO:0009245

lipid A biosynthetic process

PMID:9268317[1]

IDA: Inferred from Direct Assay

P

Fig.11

complete

GO:0009029

tetraacyldisaccharide 4'-kinase activity

PMID:9575203[2]

IMP: Inferred from Mutant Phenotype

F

Figure 9

complete

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003758

F

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

GO:0008610

lipid biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0444

P

GO:0009029

tetraacyldisaccharide 4'-kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003758

F

GO:0009029

tetraacyldisaccharide 4'-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.130

F

GO:0009245

lipid A biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003758

P

GO:0009245

lipid A biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0441

P

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Garrett TA et al. (1997) Identification of the gene encoding the Escherichia coli lipid A 4'-kinase. Facile phosphorylation of endotoxin analogs with recombinant LpxK. J Biol Chem 272: 21855-64 PubMed GONUTS page
  2. Garrett TA et al. (1998) Accumulation of a lipid A precursor lacking the 4'-phosphate following inactivation of the Escherichia coli lpxK gene. J Biol Chem 273: 12457-65 PubMed GONUTS page
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