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ECOLI:EMRB
Contents |
| Species (Taxon ID) | Escherichia coli (strain K12). (taxon:83333) | |
| Gene Name(s) | emrB | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | EMRB_ECOLI | |
| UniProt Accessions | P0AEJ0, P27304, P77725, | |
| EMBL | M86657, U00096, AP009048, | |
| PIR | G65048, | |
| RefSeq | AP_003258.1, NP_417171.1, | |
| Pfam | PF07690, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0037 |
C |
||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0055085 |
transmembrane transport |
ISS: Inferred from Sequence or Structural Similarity |
|
P |
Page 8940 - The hydropathy plot indicated a highly hydrophobic, integral membrane protein with 14 a-helices to span the membrane. The translated amino acid sequence appeared to be homologous to QacA. |
complete | ||
| GO:0016021 |
integral to membrane |
ISS: Inferred from Sequence or Structural Similarity |
|
C |
Page 8940 - The hydropathy plot indicated a highly hydrophobic, integral membrane protein with 14 a-helices to span the membrane. The translated amino acid sequence appeared to be homologous to QacA. |
complete | ||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0046677 |
response to antibiotic |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:2000275 |
regulation of oxidative phosphorylation uncoupler activity |
IMP: Inferred from Mutant Phenotype |
P |
Figure 3: Compares fluorescence (extrapolated to growth) of bacteria that contain EmrB and bacteria that do not. The bacteria are grown in a cultures with various levels of uncouplers. |
complete | |||
| GO:0071236 |
cellular response to antibiotic |
ISS: Inferred from Sequence or Structural Similarity |
UniProtKB:P0A0J9 UniProtKB:P27303
|
P |
Page 8940-8941: The hydropathy plot indicated a highly hydrophobic, integral membrane protein with 14 a-helices to span the membrane. The translated amino acid sequence appeared to be homologous to QacA, the pump for resistance to quaternary ammonium cations from Staphylococcus (23% identity and 54% similarity), to the Streptomyces Mmr putative peptide (23) conferring resistance to methylenomycin (26% identity and 50% similarity), and to genes conferring resistance to tetracycline in Gram-positive bacteria (24, 25). The QacA and Mmr peptides have 14 putative transmembrane segments (23) as would the EmrB peptide. |
complete | ||
| GO:0008493 |
tetracycline transporter activity |
ISS: Inferred from Sequence or Structural Similarity |
UniProtKB:P0A0J9 UniProtKB:P27303
|
F |
Page 8940-8941: The hydropathy plot indicated a highly hydrophobic, integral membrane protein with 14 a-helices to span the membrane. The translated amino acid sequence appeared to be homologous to QacA, the pump for resistance to quaternary ammonium cations from Staphylococcus (23% identity and 54% similarity), to the Streptomyces Mmr putative peptide (23) conferring resistance to methylenomycin (26% identity and 50% similarity), and to genes conferring resistance to tetracycline in Gram-positive bacteria (24, 25). The QacA and Mmr peptides have 14 putative transmembrane segments (23) as would the EmrB peptide. |
complete | ||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0037 |
C |
||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0046677 |
response to antibiotic |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0055085 |
transmembrane transport |
IEA: Inferred from Electronic Annotation |
P |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Lomovskaya O & Lewis K (1992) Emr, an Escherichia coli locus for multidrug resistance. Proc Natl Acad Sci U S A 89: 8938-42 PubMed GONUTS page
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