ECOLI:ACP

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Species (Taxon ID)	Escherichia coli (strain K12). (taxon:83333)
Gene Name(s)	acpP
Protein Name(s)	Acyl carrier protein ACP Cytosolic-activating factor CAF Fatty acid synthase acyl carrier protein
External Links
UniProt Identifier	ACP_ECOLI
UniProt Accessions	P0A6A8, P02901, Q53352,
EMBL	M84991, S65033, U00096, AP009048, Z34979,
PIR	C42147,
RefSeq	AP_001720.1, NP_415612.1,
PDB	1ACP, 1L0H, 1L0I, 1T8K, 2FAC, 2FAD, 2FAE, 2FHS, 2K92, 2K93, 2K94, 3EJB, 3EJD, 3EJE,
IntAct	P0A6A8,
Pfam	PF00550,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect
	GO:0000035	acyl binding	PMID:15459190^[1]	IDA: Inferred from Direct Assay		F
	GO:0000036	acyl carrier activity	PMID:15459190^[1]	IDA: Inferred from Direct Assay		F
	GO:0000036	acyl carrier activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003231	F
	GO:0000036	acyl carrier activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009081	F
	GO:0005737	cytoplasm	PMID:15459190^[1]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:16858726^[2]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C
	GO:0006633	fatty acid biosynthetic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003231	P
	GO:0006633	fatty acid biosynthetic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0275	P
	GO:0006633	fatty acid biosynthetic process	PMID:16352845^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0008610	lipid biosynthetic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0444	P
	GO:0008610	lipid biosynthetic process	PMID:16352845^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0009245	lipid A biosynthetic process	PMID:16352845^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0031177	phosphopantetheine binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006162	F
	GO:0031177	phosphopantetheine binding	PMID:16352845^[3]	IMP: Inferred from Mutant Phenotype		F
	GO:0042493	response to drug	PMID:15459190^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0048037	cofactor binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006163	F
	GO:0000036	acyl carrier activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009081	F
	GO:0005737	cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C
	GO:0005737	cytoplasm	PMID:16858726^[2]	IDA: Inferred from Direct Assay		C
	GO:0006633	fatty acid biosynthetic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003231	P
	GO:0006633	fatty acid biosynthetic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0275	P
	GO:0008610	lipid biosynthetic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0444	P
	GO:0031177	phosphopantetheine binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006162	F
	GO:0048037	cofactor binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006163	F
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Zhang YM et al. (2004) Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites. J Biol Chem 279: 50969-75 PubMed GONUTS page
↑ ^2.0 ^2.1 Lasserre JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27: 3306-21 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 De Lay NR & Cronan JE (2006) Gene-specific random mutagenesis of Escherichia coli in vivo: isolation of temperature-sensitive mutations in the acyl carrier protein of fatty acid synthesis. J Bacteriol 188: 287-96 PubMed GONUTS page

[PMID:15459190-0] 1.0 ^1.1 ^1.2 ^1.3 Zhang YM et al. (2004) Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites. J Biol Chem 279: 50969-75 PubMed GONUTS page

[PMID:16858726-1] 2.0 ^2.1 Lasserre JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27: 3306-21 PubMed GONUTS page

[PMID:16352845-2] 3.0 ^3.1 ^3.2 ^3.3 De Lay NR & Cronan JE (2006) Gene-specific random mutagenesis of Escherichia coli in vivo: isolation of temperature-sensitive mutations in the acyl carrier protein of fatty acid synthesis. J Bacteriol 188: 287-96 PubMed GONUTS page

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ECOLI:ACP

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