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DROME:TITIN
Contents |
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | sls (synonyms: titin) | |
| Protein Name(s) | Titin
D-Titin Kettin | |
| External Links | ||
| UniProt | Q9I7U4 | |
| EMBL | AB026845 AJ238575 AJ238577 AJ271740 AJ400900 AJ400901 AJ400902 AE014296 AE014296 AF045775 AF045776 AF045777 AF045778 AJ245406 AJ012279 AJ012280 AF135062 AF135167 AF241648 AF241649 BK000146 AY094749 | |
| PIR | S35341 | |
| RefSeq | NP_524676.2 NP_652705.2 | |
| UniGene | Dm.2974 | |
| ProteinModelPortal | Q9I7U4 | |
| IntAct | Q9I7U4 | |
| MINT | MINT-1723019 | |
| STRING | Q9I7U4 | |
| EnsemblMetazoa | FBtr0072849 | |
| GeneID | 44013 | |
| KEGG | dme:Dmel_CG1915 | |
| NMPDR | fig|7227.3.peg.7701 | |
| CTD | 44013 | |
| FlyBase | FBgn0086906 | |
| eggNOG | inNOG06026 | |
| GeneTree | EMGT00050000000317 | |
| InParanoid | Q9I7U4 | |
| OrthoDB | EOG4MW6MV | |
| PhylomeDB | Q9I7U4 | |
| NextBio | 836598 | |
| ArrayExpress | Q9I7U4 | |
| Bgee | Q9I7U4 | |
| GermOnline | CG1915 | |
| GO | GO:0000794 GO:0005875 GO:0030018 GO:0003779 GO:0003676 GO:0008307 GO:0051301 GO:0040011 GO:0007498 GO:0007076 GO:0016203 GO:0007520 GO:0045214 GO:0007062 GO:0007525 GO:0007522 | |
| InterPro | IPR010939 IPR003961 IPR007110 IPR013783 IPR013098 IPR003599 IPR003598 IPR012337 IPR001452 | |
| Gene3D | G3DSA:2.60.40.10 | |
| Pfam | PF06582 PF00041 PF07679 PF00018 | |
| SMART | SM00060 SM00409 SM00408 SM00326 | |
| SUPFAM | SSF49265 SSF53098 SSF50044 | |
| PROSITE | PS50853 PS50835 PS50002 PS50005 PS50293 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000794 |
condensed nuclear chromosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0003676 |
nucleic acid binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003779 |
actin binding |
IMP: Inferred from Mutant Phenotype |
|
F |
Seeded From UniProt |
|||
| GO:0003779 |
actin binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0468 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005875 |
microtubule associated complex |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0007049 |
cell cycle |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007062 |
sister chromatid cohesion |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007067 |
mitosis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007076 |
mitotic chromosome condensation |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007076 |
mitotic chromosome condensation |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007498 |
mesoderm development |
IEP: Inferred from Expression Pattern |
|
P |
Seeded From UniProt |
|||
| GO:0007517 |
muscle organ development |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007519 |
skeletal muscle tissue development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007519 |
skeletal muscle tissue development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007520 |
myoblast fusion |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007520 |
myoblast fusion |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007522 |
visceral muscle development |
IEP: Inferred from Expression Pattern |
|
P |
Seeded From UniProt |
|||
| GO:0007525 |
somatic muscle development |
IEP: Inferred from Expression Pattern |
|
P |
Seeded From UniProt |
|||
| GO:0008307 |
structural constituent of muscle |
IMP: Inferred from Mutant Phenotype |
|
F |
Seeded From UniProt |
|||
| GO:0016203 |
muscle attachment |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0030017 |
sarcomere |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030017 |
sarcomere |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030017 |
sarcomere |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030018 |
Z disc |
IMP: Inferred from Mutant Phenotype |
|
C |
Seeded From UniProt |
|||
| GO:0030018 |
Z disc |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030018 |
Z disc |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030018 |
Z disc |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030018 |
Z disc |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0040011 |
locomotion |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0045214 |
sarcomere organization |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0045214 |
sarcomere organization |
IGI: Inferred from Genetic Interaction |
FB:FBgn0014863 |
P |
Seeded From UniProt |
|||
| GO:0051301 |
cell division |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
| |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Machado C et al. (1998) Human autoantibodies reveal titin as a chromosomal protein. J Cell Biol 141: 321-33 PubMed GONUTS page
- ↑ 2.0 2.1 Kolmerer B et al. (2000) Sequence and expression of the kettin gene in Drosophila melanogaster and Caenorhabditis elegans. J Mol Biol 296: 435-48 PubMed GONUTS page
- ↑ 3.0 3.1 van Straaten M et al. (1999) Association of kettin with actin in the Z-disc of insect flight muscle. J Mol Biol 285: 1549-62 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Machado C & Andrew DJ (2000) D-Titin: a giant protein with dual roles in chromosomes and muscles. J Cell Biol 151: 639-52 PubMed GONUTS page
- ↑ Furlong EE et al. (2001) Patterns of gene expression during Drosophila mesoderm development. Science 293: 1629-33 PubMed GONUTS page
- ↑ Dworak HA & Sink H (2002) Myoblast fusion in Drosophila. Bioessays 24: 591-601 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Hakeda S et al. (2000) Requirements of Kettin, a giant muscle protein highly conserved in overall structure in evolution, for normal muscle function, viability, and flight activity of Drosophila. J Cell Biol 148: 101-14 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Zhang Y et al. (2000) Drosophila D-titin is required for myoblast fusion and skeletal muscle striation. J Cell Sci 113 ( Pt 17): 3103-15 PubMed GONUTS page
- ↑ Ayme-Southgate A et al. (2004) Assembly of the giant protein projectin during myofibrillogenesis in Drosophila indirect flight muscles. BMC Cell Biol 5: 17 PubMed GONUTS page
- ↑ Hudson AM et al. (2008) Mononuclear muscle cells in Drosophila ovaries revealed by GFP protein traps. Dev Biol 314: 329-40 PubMed GONUTS page
- ↑ Clark KA et al. (2007) The Drosophila muscle LIM protein, Mlp84B, cooperates with D-titin to maintain muscle structural integrity. J Cell Sci 120: 2066-77 PubMed GONUTS page
