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DROME:SPT6H

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Contents

Species (Taxon ID) Drosophila melanogaster (Fruit fly). (taxon:7227)
Gene Name(s) Spt6
Protein Name(s)
  • Transcription elongation factor SPT6
External Links
UniProt Identifier SPT6H_DROME
UniProt Accessions Q9W420, Q960J2, Q9U8B5, Q9U8B6,
EMBL AF104400, AF104401, AE014298, AY052030,
RefSeq NP_651962.2,
Pfam PF00575,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0035101

FACT complex

PMID:12934007[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q05344

C

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006641

P

GO:0005703

polytene chromosome puff

PMID:11040217[2]

IDA: Inferred from Direct Assay

C

GO:0003723

RNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003029

F

GO:0005703

polytene chromosome puff

PMID:11040216[3]

IDA: Inferred from Direct Assay

C

GO:0003711

transcription elongation regulator activity

PMID:12490954[4]

NAS: Non-traceable Author Statement

F

GO:0008023

transcription elongation factor complex

PMID:12934007[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9V460

C

GO:0005700

polytene chromosome

PMID:12490954[4]

IDA: Inferred from Direct Assay

C

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

GO:0002805

regulation of antimicrobial peptide biosynthetic process

PMID:20421637[5]

IMP: Inferred from Mutant Phenotype

P

GO:0005705

polytene chromosome interband

PMID:11040216[3]

IDA: Inferred from Direct Assay

C

GO:0016788

hydrolase activity, acting on ester bonds

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006641

F

GO:0003711

transcription elongation regulator activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017072

F

GO:0000176

nuclear exosome (RNase complex)

PMID:12490954[4]

IPI: Inferred from Physical Interaction

C

GO:0032784

regulation of transcription elongation, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017072

P

GO:0006366

transcription from RNA polymerase II promoter

PMID:11040216[3]

IEP: Inferred from Expression Pattern

P

GO:0032784

regulation of transcription elongation, DNA-dependent

PMID:12490954[4]

NAS: Non-traceable Author Statement

P

GO:0006354

transcription elongation, DNA-dependent

PMID:12490954[4]

NAS: Non-traceable Author Statement

P

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017072

P

GO:0005703

polytene chromosome puff

PMID:12934007[1]

IDA: Inferred from Direct Assay

C

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

GO:0002805

regulation of antimicrobial peptide biosynthetic process

PMID:20421637[5]

IMP: Inferred from Mutant Phenotype

P

GO:0003723

RNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003029

F

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

GO:0005703

polytene chromosome puff

PMID:11040216[3]

IDA: Inferred from Direct Assay

C

GO:0005703

polytene chromosome puff

PMID:11040217[2]

IDA: Inferred from Direct Assay

C

GO:0005703

polytene chromosome puff

PMID:12934007[1]

IDA: Inferred from Direct Assay

C

GO:0005705

polytene chromosome interband

PMID:11040216[3]

IDA: Inferred from Direct Assay

C

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006641

P

GO:0006351

transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017072

P

GO:0006366

transcription from RNA polymerase II promoter

PMID:11040216[3]

IEP: Inferred from Expression Pattern

P

GO:0008023

transcription elongation factor complex

PMID:12934007[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9V460

C

GO:0016788

hydrolase activity, acting on ester bonds

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006641

F

GO:0032784

regulation of transcription elongation, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017072

P

GO:0035327

transcriptionally active chromatin

PMID:12490954[4]

IDA: Inferred from Direct Assay

C

GO:0035363

histone locus body

PMID:21576393[6]

IDA: Inferred from Direct Assay

C

colocalizes_with

GO:0000176

nuclear exosome (RNase complex)

PMID:12490954[4]

IDA: Inferred from Direct Assay

C

colocalizes_with

GO:0035101

FACT complex

PMID:12934007[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q05344

C


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Saunders A et al. (2003) Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo. Science 301: 1094-6 PubMed GONUTS page
  2. 2.0 2.1 Andrulis ED et al. (2000) High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation. Genes Dev 14: 2635-49 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Kaplan CD et al. (2000) Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster. Genes Dev 14: 2623-34 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Andrulis ED et al. (2002) The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila. Nature 420: 837-41 PubMed GONUTS page
  5. 5.0 5.1 Valanne S et al. (2010) Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling. J Immunol 184: 6188-98 PubMed GONUTS page
  6. White AE et al. (2011) Drosophila histone locus bodies form by hierarchical recruitment of components. J Cell Biol 193: 677-94 PubMed GONUTS page
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