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DROME:CP314

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Contents

Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) shd (synonyms: CYP314A1)
Protein Name(s) Ecdysone 20-monooxygenase

E20MO CYPCCCXIVA1 Cytochrome P450 314a1, mitochondrial Protein shade

External Links
UniProt Q9VUF8
EMBL AF484414
AE014296
AE014296
AY089309
RefSeq NP_996074.1
UniGene Dm.5109
ProteinModelPortal Q9VUF8
SMR Q9VUF8
STRING Q9VUF8
PRIDE Q9VUF8
EnsemblMetazoa FBtr0075676
GeneID 39592
KEGG dme:Dmel_CG13478
UCSC CG13478-RA
CTD 56961
FlyBase FBgn0003388
eggNOG inNOG07210
GeneTree EMGT00050000001200
InParanoid Q9VUF8
OMA KACIQES
OrthoDB EOG4WDBT3
PhylomeDB Q9VUF8
BioCyc MetaCyc:MONOMER-7726
BRENDA 1.14.99.22
NextBio 814420
ArrayExpress Q9VUF8
Bgee Q9VUF8
GermOnline CG13478
GO GO:0031966
GO:0004501
GO:0009055
GO:0020037
GO:0007417
GO:0007391
GO:0045456
GO:0007295
GO:0008258
GO:0007494
InterPro IPR001128
IPR017972
IPR002401
Gene3D G3DSA:1.10.630.10
KO K10723
Pfam PF00067
PRINTS PR00463
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004497

monooxygenase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0503

F

Seeded From UniProt

GO:0004501

ecdysone 20-monooxygenase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.14.99.22

F

Seeded From UniProt

GO:0004501

ecdysone 20-monooxygenase activity

PMID:14610274[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0005506

iron ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001128

F

Seeded From UniProt

GO:0005506

iron ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002401

F

Seeded From UniProt

GO:0005739

mitochondrion

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0496

C

Seeded From UniProt

GO:0005739

mitochondrion

PMID:14610274[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0007295

growth of a germarium-derived egg chamber

PMID:14610274[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0007391

dorsal closure

PMID:12676319[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0007391

dorsal closure

PMID:14610274[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0007417

central nervous system development

PMID:12676319[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0007494

midgut development

PMID:14610274[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0008258

head involution

PMID:12676319[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0009055

electron carrier activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001128

F

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded From UniProt

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001128

F

Seeded From UniProt

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002401

F

Seeded From UniProt

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017972

F

Seeded From UniProt

GO:0020037

heme binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001128

F

Seeded From UniProt

GO:0020037

heme binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002401

F

Seeded From UniProt

GO:0031966

mitochondrial membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0171

C

Seeded From UniProt

GO:0045456

ecdysteroid biosynthetic process

PMID:14610274[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001128

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002401

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017972

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Petryk A et al. (2003) Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone. Proc Natl Acad Sci U S A 100: 13773-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 Giesen K et al. (2003) Regulation of glial cell number and differentiation by ecdysone and Fos signaling. Mech Dev 120: 401-13 PubMed GONUTS page
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