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DROME:BIB
Contents |
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | bib | |
| Protein Name(s) | Neurogenic protein big brain | |
| External Links | ||
| UniProt | P23645 | |
| EMBL | X53275 AE014134 AY051981 | |
| PIR | S09699 | |
| RefSeq | NP_476837.1 | |
| UniGene | Dm.3236 | |
| ProteinModelPortal | P23645 | |
| SMR | P23645 | |
| DIP | DIP-21188N | |
| IntAct | P23645 | |
| MINT | MINT-1607360 | |
| STRING | P23645 | |
| TCDB | 1.A.8.8.3 | |
| EnsemblMetazoa | FBtr0079929 | |
| GeneID | 34330 | |
| KEGG | dme:Dmel_CG4722 | |
| NMPDR | fig|7227.3.peg.1696 | |
| CTD | 34330 | |
| FlyBase | FBgn0000180 | |
| eggNOG | inNOG09276 | |
| GeneTree | EMGT00050000002251 | |
| InParanoid | P23645 | |
| OMA | LQNQNVQ | |
| OrthoDB | EOG46T1GV | |
| PhylomeDB | P23645 | |
| NextBio | 787982 | |
| ArrayExpress | P23645 | |
| Bgee | P23645 | |
| GermOnline | CG4722 | |
| GO | GO:0016021 GO:0005261 GO:0016337 GO:0007398 GO:0048388 GO:0007498 GO:0007399 GO:0007219 GO:0030707 GO:0006833 | |
| InterPro | IPR012269 IPR023271 IPR000425 IPR022357 | |
| Gene3D | G3DSA:1.20.1080.10 | |
| PANTHER | PTHR19139 | |
| Pfam | PF00230 | |
| PRINTS | PR00783 | |
| SUPFAM | SSF81338 | |
| TIGRFAMs | TIGR00861 | |
| PROSITE | PS00221 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005215 |
transporter activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005215 |
transporter activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005215 |
transporter activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005216 |
ion channel activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005261 |
cation channel activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006833 |
water transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007032 |
endosome organization |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007219 |
Notch signaling pathway |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007398 |
ectoderm development |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007399 |
nervous system development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007399 |
nervous system development |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007498 |
mesoderm development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0162 |
C |
Seeded From UniProt |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0016337 |
cell-cell adhesion |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0030154 |
cell differentiation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0030707 |
ovarian follicle cell development |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0048388 |
endosomal lumen acidification |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0055085 |
transmembrane transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0005216 |
ion channel activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005372 |
water transmembrane transporter activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0007398 |
IMP: Inferred from Mutant Phenotype |
The hypertrophy effect of bib is shown to have an effect on the phenotype. Figure 1. Figure 2. |
complete | |||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yanochko GM & Yool AJ (2002) Regulated cationic channel function in Xenopus oocytes expressing Drosophila big brain. J Neurosci 22: 2530-40 PubMed GONUTS page
- ↑ 2.0 2.1 Kanwar R & Fortini ME (2008) The big brain aquaporin is required for endosome maturation and notch receptor trafficking. Cell 133: 852-63 PubMed GONUTS page
- ↑ Stewart BA (2002) Membrane trafficking in Drosophila wing and eye development. Semin Cell Dev Biol 13: 91-7 PubMed GONUTS page
- ↑ 4.0 4.1 Corbin V et al. (1991) A role for the Drosophila neurogenic genes in mesoderm differentiation. Cell 67: 311-23 PubMed GONUTS page
- ↑ Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Tatsumi K et al. (2009) Drosophila big brain does not act as a water channel, but mediates cell adhesion. FEBS Lett 583: 2077-82 PubMed GONUTS page
- ↑ Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
- ↑ Rao Y et al. (1992) The big brain gene of Drosophila functions to control the number of neuronal precursors in the peripheral nervous system. Development 116: 31-40 PubMed GONUTS page
