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DAPPU:E9HT81
Contents |
| Species (Taxon ID) | Daphnia pulex (Water flea). (6669) | |
| Gene Name(s) | CCS1 | |
| Protein Name(s) | Copper chaperone for super oxide dismutase, CCS1 | |
| External Links | ||
| UniProt | E9HT81 | |
| EMBL | GL732766 | |
| OMA | CDGVTLW | |
| PhylomeDB | E9HT81 | |
| GO | GO:0046872 GO:0004784 GO:0030001 GO:0006801 | |
| InterPro | IPR006121 IPR024134 IPR024142 IPR001424 | |
| Gene3D | G3DSA:2.60.40.200 | |
| PANTHER | PTHR10003:SF27 PTHR10003 | |
| Pfam | PF00403 PF00080 | |
| PRINTS | PR00068 | |
| SUPFAM | SSF55008 SSF49329 | |
| PROSITE | PS50846 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0006801 |
superoxide metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006801 |
superoxide metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0030001 |
metal ion transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0015677 |
copper ion import |
IMP: Inferred from Mutant Phenotype |
P |
fig. 1: copper chaperone for Sod1 (Ccs1) We identified two cysteines (Cys-27 and Cys-64) in domain I that are required for mitochondrial import of Ccs1—but not for its role in Sod1 maturation—by the use of cysteine mutants. |
complete | |||
| GO:0018316 |
peptide cross-linking via L-cystine |
IMP: Inferred from Mutant Phenotype |
P |
fig 2C: we found that the C27–C64 disulfide was formed in the presence of Mia40-WT. Of importance, in the absence of functional Mia40 no oxidation of the two cysteines occurred |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Klöppel C et al. (2011) Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol. Mol Biol Cell 22: 3749-57 PubMed GONUTS page
