Category:PTHR11361:AN79

Contents 1 Graphs 2 Summary Table 3 Annotations inferred for PTHR11361:AN79 4 Notes 5 References

Graphs

Cellular Component graph

RefGenome graph at MGI.

Biological Process graph

RefGenome graph at MGI.

Molecular Function graph

RefGenome graph at MGI.

Summary Table

Aspect	ID	Term	SCHPO MSH6	WB msh‑6	ZFIN msh6	dictyBase msh6	FB Msh6	HUMAN MSH6	SGD MSH6
Biological Process	GO:0000710	meiotic mismatch repair	ISS				IMP	ISS	IMP
Biological Process	GO:0003006	reproductive developmental process						ISS-An
Biological Process	GO:0006281	DNA repair					ISS	IDA
Biological Process	GO:0006298	mismatch repair	IMP	IMP		ISS		IDA  IMP  ISS-An	IDA  IMP
Biological Process	GO:0006301	postreplication repair					NAS
Biological Process	GO:0006974	response to DNA damage stimulus		IMP
Biological Process	GO:0007126	meiosis						ISS-An
Biological Process	GO:0007131	reciprocal meiotic recombination	ISS
Biological Process	GO:0008340	determination of adult life span						ISS
Biological Process	GO:0008629	induction of apoptosis by intracellular signals						ISS
Biological Process	GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis						ISS
Biological Process	GO:0009411	response to UV	ISS					ISS
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes						ISS
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments						ISS
Biological Process	GO:0043570	maintenance of DNA repeat elements	IMP	IMP	IMP			NOT IMP
Biological Process	GO:0045190	isotype switching						ISS
Biological Process	GO:0045910	negative regulation of DNA recombination	ISS					IDA
Biological Process	GO:0051096	positive regulation of helicase activity						IDA
Cellular Component	GO:0000228	nuclear chromosome	ISS
Cellular Component	GO:0000794	condensed nuclear chromosome						ISS-An
Cellular Component	GO:0005634	nucleus	IDA			ISS		ISS-An	IDA
Cellular Component	GO:0032301	MutSalpha complex	ISS	ISS		ISS		IDA	IPI
Molecular Function	GO:0000287	magnesium ion binding						contributes_to IDA
Molecular Function	GO:0000400	four-way junction DNA binding	ISS					contributes_to IDA	IDA
Molecular Function	GO:0003677	DNA binding		ISS
Molecular Function	GO:0003684	damaged DNA binding	ISS					ISS-An
Molecular Function	GO:0003690	double-stranded DNA binding			IDA			contributes_to IDA
Molecular Function	GO:0005515	protein binding						IPI contributes_to IPI
Molecular Function	GO:0005524	ATP binding	ISS			ISS		contributes_to IDA	IDA
Molecular Function	GO:0008094	DNA-dependent ATPase activity	ISS
Molecular Function	GO:0016887	ATPase activity				ISS		contributes_to IDA	IDA
Molecular Function	GO:0030983	mismatched DNA binding			IDA	contributes_to ISS		ISS-An contributes_to IDA
Molecular Function	GO:0032134	mispaired DNA binding						contributes_to IDA
Molecular Function	GO:0032137	guanine/thymine mispair binding	ISS		IGI			contributes_to IDA	contributes_to IDA
Molecular Function	GO:0032138	single base insertion or deletion binding	ISS						contributes_to IDA contributes_to IMP
Molecular Function	GO:0032142	single guanine insertion binding						contributes_to IDA
Molecular Function	GO:0032143	single thymine insertion binding						contributes_to IDA
Molecular Function	GO:0032357	oxidized purine DNA binding						contributes_to IDA
Molecular Function	GO:0032405	MutLalpha complex binding						contributes_to IDA
Molecular Function	GO:0042803	protein homodimerization activity						NOT IPI
Molecular Function	GO:0043531	ADP binding						contributes_to IDA
Cellular Component	GO:0005829	cytosol	IDA

Annotations inferred for PTHR11361:AN79

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0003684	damaged DNA binding	PMID:17208035[1]	ISS: Inferred from Sequence or Structural Similarity	MGI=MGI=1343961 TAIR=locus=2132233 ENSEMBL=ENSG00000116062	F	Seeded From PANTHER
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Notes

References

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1. ↑ Thomas PD et al. (2007) Ontology annotation: mapping genomic regions to biological function. Curr Opin Chem Biol 11: 4-11 PubMed GONUTS page