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Category:GO:1990333 ! mitotic checkpoint complex, CDC20-MAD2 subcomplex
name: mitotic checkpoint complex, CDC20-MAD2 subcomplex
namespace: cellular_component
def: "A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20." [GOC:bhm, PMID:15879521]
comment: An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).
synonym: "CDC20-MAD2 complex" EXACT []
is_a: GO:0140513 ! nuclear protein-containing complex
relationship: part_of: GO:0033597 ! mitotic checkpoint complex
AmiGO
<GOterm>GO:1990333</GOterm>
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