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Category:GO:0097345 ! mitochondrial outer membrane permeabilization
name: mitochondrial outer membrane permeabilization
namespace: biological_process
def: "The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:pg, PMID:21041309]
comment: BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).
synonym: "mitochondrial outer membrane permeabilization during apoptotic cell death" BROAD []
synonym: "mitochondrion outer membrane permeabilization" EXACT []
synonym: "MOMP" EXACT []
is_a: GO:1902110 ! positive regulation of mitochondrial membrane permeability involved in apoptotic process
relationship: part_of: GO:0097190 ! apoptotic signaling pathway
AmiGO
<GOterm>GO:0097345</GOterm>
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This category has the following 3 subcategories, out of 3 total.
