GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:GO:0097191 ! extrinsic apoptotic signaling pathway

From GONUTS
Jump to: navigation, search

DAG for GO:0097191id: GO:0097191

name: extrinsic apoptotic signaling pathway
namespace: biological_process
def: "The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis, GOC:yaf, PMID:17340152]
comment: Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer.
synonym: "death receptor-mediated apoptosis" NARROW []
synonym: "extrinsic apoptosis" NARROW []
synonym: "extrinsic apoptotic pathway" EXACT []
synonym: "extrinsic apoptotic signaling pathway in presence of ligand" NARROW []
synonym: "extrinsic apoptotic signalling pathway" EXACT [GOC:mah]
is_a: GO:0007166 ! cell surface receptor signaling pathway
is_a: GO:0097190 ! apoptotic signaling pathway

AmiGO <GOterm>GO:0097191</GOterm>
Gene Ontology Home


The contents of this box are automatically generated. You can help by adding information to the "Notes"

Usage Notes

References

See Help:References for how to manage references in GONUTS.