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Category:GO:0071159 ! NF-kappaB complex
name: NF-kappaB complex
namespace: cellular_component
def: "A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression." [ISBN:0849327946]
is_a: GO:0043234 ! protein complex
is_a: GO:0044424 ! intracellular part
AmiGO
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Pages in category "GO:0071159 ! NF-kappaB complex"
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