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Category:GO:0070533 ! BRCA1-C complex
name: BRCA1-C complex
namespace: cellular_component
def: "A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint." [GOC:mah, PMID:15485915, PMID:16391231]
is_a: GO:0043234 ! protein complex
is_a: GO:0044428 ! nuclear part
AmiGO
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