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Category:GO:0070375 ! ERK5 cascade
name: ERK5 cascade
namespace: biological_process
def: "A MAPK cascade containing at least the ERK5 MAP kinase (MAPK7; also called BMK1). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK5. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The ERK5 cascade is activated by stress, mitogens, and by G protein-coupled receptors, and results in cellular responses such as cell growth, cell differentiation and development." [PMID:16376520, PMID:16880823, PMID:20811974, PMID:23125017, PMID:28903453]
synonym: "big MAP kinase signaling cascade" EXACT [PMID:20811974]
synonym: "BMK cascade" EXACT [PMID:20811974]
synonym: "BMK signaling pathway" EXACT [GOC:mah]
synonym: "BMK signalling pathway" EXACT [GOC:mah]
synonym: "BMK1 cascade" EXACT [GOC:add]
synonym: "ERK5 signaling pathway" EXACT [PMID:16376520]
synonym: "extracellular signal-regulated kinase 5 cascade" EXACT [PMID:20811974]
synonym: "MAPK7 cascade" EXACT [GOC:add]
is_a: GO:0000165 ! MAPK cascade
AmiGO
<GOterm>GO:0070375</GOterm>
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This category has the following 2 subcategories, out of 2 total.
