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Category:GO:0060397 ! JAK-STAT cascade involved in growth hormone signaling pathway
name: JAK-STAT cascade involved in growth hormone signaling pathway
namespace: biological_process
def: "The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes." [GOC:BHF, GOC:dph, PMID:11445442]
synonym: "JAK-STAT cascade involved in growth hormone signalling pathway" EXACT [GOC:dph]
xref: Reactome:REACT_111133 "Growth hormone receptor signaling, Homo sapiens"
is_a: GO:0007259 ! JAK-STAT cascade
relationship:part_of: GO:0060396 ! growth hormone receptor signaling pathway
AmiGO
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