Category:GO:0051362 ! peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine

name: peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine
namespace: biological_process
def: "The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species." [PDB:1XAE, PMID:10504696, PMID:15628861, RESID:AA0382]
comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.
synonym: "biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine" EXACT []
synonym: "biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine" EXACT []
xref: RESID:AA0382
is_a: GO:0018205 ! peptidyl-lysine modification
is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine
is_a: GO:0018298 ! protein-chromophore linkage

AmiGO