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Category:GO:0050501 ! hyaluronan synthase activity
name: hyaluronan synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP." [EC:2.4.1.212, MetaCyc:2.4.1.212-RXN]
subset: gosubset_prok
synonym: "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212]
synonym: "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212]
synonym: "HAS activity" BROAD [EC:2.4.1.212]
synonym: "seHAS" RELATED [EC:2.4.1.212]
synonym: "spHAS" RELATED [EC:2.4.1.212]
xref: EC:2.4.1.212
xref: MetaCyc:2.4.1.212-RXN
is_a: GO:0008194 ! UDP-glycosyltransferase activity
is_a: GO:0016758 ! transferase activity, transferring hexosyl groups
AmiGO
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