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Category:GO:0047787 ! delta4-3-oxosteroid 5beta-reductase activity
name: delta4-3-oxosteroid 5beta-reductase activity
namespace: molecular_function
alt_id: GO:0047752
def: "Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+." [EC:1.3.1.3, MetaCyc:CORTISONE-BETA-REDUCTASE-RXN]
synonym: "3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity" RELATED [EC:1.3.1.23]
synonym: "3-oxo-Delta(4)-steroid 5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "3-oxo-delta4-steroid 5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity" RELATED [EC:1.3.1.23]
synonym: "5-beta-reductase activity" BROAD [EC:1.3.1.23]
synonym: "5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity" RELATED [EC:1.3.1.23]
synonym: "5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "androstenedione 5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "androstenedione 5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "cholestenone 5-beta-reductase activity" EXACT []
synonym: "cholestenone 5b-reductase activity" EXACT []
synonym: "cholestenone 5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "cortisone 5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "cortisone 5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "cortisone b-reductase activity" EXACT []
synonym: "cortisone beta-reductase activity" EXACT []
synonym: "cortisone delta(4)-5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "cortisone delta4-5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "delta(4)-3-ketosteroid 5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "delta(4)-5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "delta(4)-hydrogenase activity" RELATED [EC:1.3.1.23]
synonym: "delta4-3-ketosteroid 5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "delta4-3-oxosteroid 5-beta-reductase activity" EXACT []
synonym: "delta4-5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "delta4-hydrogenase activity" RELATED [EC:1.3.1.23]
synonym: "steroid 5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "steroid 5beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "testosterone 5-beta-reductase activity" RELATED [EC:1.3.1.23]
synonym: "testosterone 5beta-reductase activity" RELATED [EC:1.3.1.23]
xref: EC:1.3.1.3
xref: MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN
xref: MetaCyc:CORTISONE-BETA-REDUCTASE-RXN
xref: MetaCyc:RXN-9726
is_a: GO:0035671 ! enone reductase activity
AmiGO
<GOterm>GO:0047787</GOterm>
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