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Category:GO:0046820 ! 4-amino-4-deoxychorismate synthase activity
name: 4-amino-4-deoxychorismate synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate." [EC:2.6.1.85, RHEA:11675]
comment: Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.
subset: gosubset_prok
synonym: "ADC synthase activity" EXACT [EC:2.6.1.85]
synonym: "aminodeoxychorismate synthase activity" RELATED []
synonym: "chorismate:L-glutamine amido-ligase activity" EXACT [EC:2.6.1.85]
synonym: "p-aminobenzoate synthetase" RELATED []
synonym: "PabB activity" RELATED [EC:2.6.1.85]
synonym: "para-aminobenzoic acid (PABA) synthase" RELATED []
synonym: "para-aminobenzoic acid synthase activity" RELATED []
xref: EC:2.6.1.85
xref: KEGG:R01716
xref: MetaCyc:PABASYN-RXN
xref: RHEA:11675
is_a: GO:0008483 ! transaminase activity
AmiGO
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