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Category:GO:0045254 ! pyruvate dehydrogenase complex
name: pyruvate dehydrogenase complex
namespace: cellular_component
alt_id:GO:0009364
def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3)." [ISBN:0716720094]
comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.
subset: goslim_pir
subset: gosubset_prok
synonym: "dihydrolipoyl dehydrogenase complex" BROAD []
synonym: "pyruvate dehydrogenase complex (lipoamide)" EXACT []
xref: Wikipedia:Pyruvate_dehydrogenase_complex
is_a: GO:0043234 ! protein complex
is_a: GO:0044444 ! cytoplasmic part
AmiGO
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This term has the following 3 child terms, out of 3 total.
