Category:GO:0043687 ! post-translational protein modification

name: post-translational protein modification
namespace: biological_process
def: "The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome." [GOC:jsg]
comment: This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
subset: gosubset_prok
synonym: "post-translational amino acid modification" EXACT []
synonym: "post-translational modification" EXACT []
synonym: "posttranslational amino acid modification" EXACT []
synonym: "posttranslational modification" EXACT []
synonym: "posttranslational protein modification" EXACT []
synonym: "PTM" EXACT []
xref: Reactome:REACT_100887 "Post-translational protein modification, Canis familiaris"
xref: Reactome:REACT_101114 "Post-translational protein modification, Arabidopsis thaliana"
xref: Reactome:REACT_103281 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Saccharomyces cerevisiae"
xref: Reactome:REACT_103494 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Schizosaccharomyces pombe"
xref: Reactome:REACT_104966 "Post-translational protein modification, Saccharomyces cerevisiae"
xref: Reactome:REACT_105450 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Danio rerio"
xref: Reactome:REACT_1069 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Homo sapiens"
xref: Reactome:REACT_109761 "Post-translational protein modification, Gallus gallus"
xref: Reactome:REACT_113592 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Caenorhabditis elegans"
xref: Reactome:REACT_22161 "Post-translational protein modification, Homo sapiens"
xref: Reactome:REACT_29658 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Gallus gallus"
xref: Reactome:REACT_31587 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Drosophila melanogaster"
xref: Reactome:REACT_31741 "Post-translational protein modification, Dictyostelium discoideum"
xref: Reactome:REACT_33179 "Post-translational protein modification, Danio rerio"
xref: Reactome:REACT_33269 "Post-translational protein modification, Taeniopygia guttata"
xref: Reactome:REACT_33662 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Oryza sativa"
xref: Reactome:REACT_34647 "Post-translational protein modification, Xenopus tropicalis"
xref: Reactome:REACT_78360 "Post-translational protein modification, Sus scrofa"
xref: Reactome:REACT_78573 "Post-translational protein modification, Caenorhabditis elegans"
xref: Reactome:REACT_81500 "Post-translational protein modification, Schizosaccharomyces pombe"
xref: Reactome:REACT_81635 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Mus musculus"
xref: Reactome:REACT_82133 "Post-translational protein modification, Bos taurus"
xref: Reactome:REACT_82385 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Xenopus tropicalis"
xref: Reactome:REACT_83056 "Post-translational protein modification, Plasmodium falciparum"
xref: Reactome:REACT_83451 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Taeniopygia guttata"
xref: Reactome:REACT_83761 "Post-translational protein modification, Drosophila melanogaster"
xref: Reactome:REACT_85268 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Sus scrofa"
xref: Reactome:REACT_87023 "Post-translational protein modification, Mus musculus"
xref: Reactome:REACT_88089 "Post-translational protein modification, Rattus norvegicus"
xref: Reactome:REACT_88325 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Canis familiaris"
xref: Reactome:REACT_89018 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Rattus norvegicus"
xref: Reactome:REACT_91093 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Bos taurus"
xref: Reactome:REACT_91222 "Post-translational protein modification, Oryza sativa"
xref: Reactome:REACT_91597 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Arabidopsis thaliana"
xref: Reactome:REACT_96864 "PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, Dictyostelium discoideum"
xref: Wikipedia:Posttranslational_modification
is_a: GO:0006464 ! protein modification process

AmiGO

Child Terms

This term has the following 6 child terms, out of 6 total.

• [  ] GO:0001318 ! formation of oxidatively modified proteins during replicative cell aging
• [+] GO:0018410 ! C-terminal protein amino acid modification (5)
• [+] GO:0018410 ! peptide or protein carboxyl-terminal blocking (1)
• [  ] GO:0034421 ! post-translational protein acetylation
• [  ] GO:0034421 ! post-translational protein amino acid acetylation
• [  ] GO:0071587 ! CAAX-box protein modification

Pages in category "GO:0043687 ! post-translational protein modification"

The following 62 pages are in this category, out of 62 total.