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Category:GO:0043564 ! Ku70:Ku80 complex
name: Ku70:Ku80 complex
namespace: cellular_component
def: "Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK." [PMID:12518983]
synonym: "Ku70:Ku80 heterodimer" EXACT []
is_a: GO:0043234 ! protein complex
is_a: GO:0044428 ! nuclear part
AmiGO
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