Category:GO:0042533 ! tumor necrosis factor biosynthetic process

name: tumor necrosis factor biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884]
comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').
synonym: "TNF alpha biosynthesis" EXACT []
synonym: "TNF alpha biosynthetic process" EXACT []
synonym: "TNF biosynthesis" EXACT []
synonym: "TNF biosynthetic process" EXACT []
synonym: "TNF-alpha biosynthesis" EXACT []
synonym: "TNF-alpha biosynthetic process" EXACT []
synonym: "Tumor Necrosis Factor alpha biosynthesis" EXACT []
synonym: "Tumor Necrosis Factor alpha biosynthetic process" EXACT []
synonym: "tumor necrosis factor anabolism" EXACT []
synonym: "tumor necrosis factor biosynthesis" EXACT []
synonym: "tumor necrosis factor formation" EXACT []
synonym: "tumor necrosis factor synthesis" EXACT []
is_a: GO:0042089 ! cytokine biosynthetic process
relationship:part_of: GO:0032640 ! tumor necrosis factor production

AmiGO

Child Terms

This term has the following 3 child terms, out of 3 total.

• [+] GO:0042534 ! regulation of tumor necrosis factor biosynthetic process (2)
• [  ] GO:0042535 ! positive regulation of tumor necrosis factor biosynthetic process
• [  ] GO:0042536 ! negative regulation of tumor necrosis factor biosynthetic process