Category:GO:0042380 ! hydroxymethylbutenyl pyrophosphate reductase activity

name: hydroxymethylbutenyl pyrophosphate reductase activity
namespace: molecular_function
def: "Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate." [GOC:js]
comment: Note that the enzyme performing this function has only recently been characterized, and not completely (see PMID:11818558). The common and systematic names have been suggested by TIGR, who have recently compiled an HMM model for this gene (TIGR00216). The enzyme appears to catalyze the final step in the non-mevalonate terpene biosynthesis pathway. Its two products, isopentenyl pyrophosphate and dimethylallyl pyrophosphate, are apparently generated from a common intermediate formed by the enzyme. The mechanism and identity of the reductant have not yet been determined.
subset: gosubset_prok
synonym: "(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)" EXACT []
is_a: GO:0016491 ! oxidoreductase activity

AmiGO