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Category:GO:0039529 ! RIG-I signaling pathway
name: RIG-I signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines." [GOC:bf, PMID:17328678, PMID:19620789, PMID:21435580, PMID:25579795]
synonym: "DDX58 signaling pathway" EXACT [HGNC:19102]
synonym: "retinoic acid inducible gene I signaling pathway" EXACT [HGNC:19102]
synonym: "RIG-I signalling pathway" EXACT [GOC:mah]
synonym: "RIG-I-like receptor (RLR) signaling pathway" EXACT []
synonym: "RIG-like helicase signaling pathway" EXACT []
synonym: "RIG-like receptor signaling pathway" EXACT []
synonym: "RLH signaling pathway" EXACT []
synonym: "RLR signaling pathway" EXACT []
is_a: GO:0002753 ! cytoplasmic pattern recognition receptor signaling pathway
AmiGO
<GOterm>GO:0039529</GOterm>
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This category has the following 2 subcategories, out of 2 total.
